Results 211 to 220 of about 2,467,569 (240)
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2016
Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide ...
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Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide ...
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Association Studies in Genetics
2011This chapter is devoted at first to a quick review of case control studies in genetic epidemiology. The case–control method is usually applied in genetic epidemiology to elucidate the role of genetic factors and their interaction with environmental factors in the aetiology of human diseases.
Luigi Salmaso +3 more
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Detecting Sample Misidentifications in Genetic Association Studies
Statistical Applications in Genetics and Molecular Biology, 2012Genetic association studies require that the genotype data from a given person can be correctly linked to the phenotype data from the same person. However, sample misidentification errors sometimes happen, whereby the link becomes invalid for some of the subjects in a study.
Ekstrøm, Claus Thorn, Feenstra, B
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Methodological issues of genetic association studies
Clinical Chemistry and Laboratory Medicine, 2010Genetic association studies explore the association between genetic polymorphisms and a certain trait, disease or predisposition to disease. It has long been acknowledged that many genetic association studies fail to replicate their initial positive findings. This raises concern about the methodological quality of these reports.
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Genetic association studies in β-hemoglobinopathies
Hematology, 2013AbstractCharacterization of the molecular basis of the β-thalassemias and sickle cell disease (SCD) clearly showed that individuals with the same β-globin genotypes can have extremely diverse clinical severity. Two key modifiers, an innate ability to produce fetal hemoglobin and coinheritance of α-thalassemia, both derived from family and population ...
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Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Veda N Giri, Todd M Morgan, David Morris
exaly
Benefits and limitations of genome-wide association studies
Nature Reviews Genetics, 2019Vivian Tam, Yohan Bossé, Guillaume Pare
exaly