Results 271 to 280 of about 931,040 (332)

Mistranslating the genetic code with leucine in yeast and mammalian cells. [PDF]

RNA Biol
Davey-Young J, Hasan F, Tennakoon R, Rozik P, Moore H, Hall P, Cozma E, Genereaux J, Hoffman KS, Chan PP, Lowe TM, Brandl CJ, O'Donoghue P.   +12 more
europepmc   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

Author Correction: RNA editing of BFP, a point mutant of GFP, using artificial APOBEC1 deaminase to restore the genetic code. [PDF]

Sci Rep
Bhakta S, Sakari M, Tsukahara T.
europepmc   +1 more source

A robust platform streamlining aromatic noncanonical amino acid biosynthesis and genetic code expansion inEscherichia coli

Zhang J, Yu K, Xu Y, Zhao W, Li Y, Wang Y, Seebeck FP, Chen X, Liao C.   +8 more
europepmc   +1 more source

Genetic Code Expansion for Mechanistic Studies in Ion Channels: An (Un)natural Union of Chemistry and Biology. [PDF]

Chem Rev
Infield DT, Schene ME, Galpin JD, Ahern CA.   +3 more
europepmc   +1 more source

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. [PDF]

J Am Chem Soc
Vinogradov AA, Zhang Y, Hamada K, Kobayashi S, Ogata K, Sengoku T, Goto Y, Suga H.   +7 more
europepmc   +1 more source

In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code. [PDF]

BMC Genomics
Opperdoes FR, Záhonová K, Škodová-Sveráková I, Bučková B, Chmelová Ľ, Lukeš J, Yurchenko V.   +6 more
europepmc   +1 more source

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THE GENETIC CODE

British Medical Bulletin, 1965
Each DNA molecule, in most preparations, contains 104 complementary nucleotide pairs and, in the large bacteriophage DNA, nearer 105 such pairs. Thus within any one molecule of DNA there are at least 410,000 that is 106,000, possible sequences of nucleotides along each of the strands.
A. R. Peacocke, R. B. Drysdale
openaire   +4 more sources