Results 281 to 290 of about 931,040 (332)
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Chemical Communications, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
Lei Wang, Peter G. Schultz
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Lei Wang, Peter G. Schultz
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Evolutionary Anthropology: Issues, News, and Reviews, 2005 The DNA-based code for protein through messenger and transfer RNA is widely regarded as the code of life. But genomes are littered with other kinds of coding elements as well, and all of them probably came after a supercode for the tRNA system itself.
Kenneth M. Weiss, Anne V. Buchanan
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Scientific American, 1962
(a) The nature of the problem Genes are made of nucleic acid. Enzymes are made of protein. The amino acid sequence of a particular protein is synthesized under instruction from a particular piece of nucleic acid. Each protein is made of one or more polypeptide chains, synthesized by con?
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(a) The nature of the problem Genes are made of nucleic acid. Enzymes are made of protein. The amino acid sequence of a particular protein is synthesized under instruction from a particular piece of nucleic acid. Each protein is made of one or more polypeptide chains, synthesized by con?
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Genetics and the Origin of the Genetic Code
Origins of Life, 1974The genetic code has been analysed by a method similar to that used by Gregor Mendel. The current codon catalogue is shown to be symmetrically subdivisible into two discrete subcatalogues of eight quartets each by classifying the quartets as monocoding (for one amino acid only) vs heterocoding (for two amino acids or for amino acid plus nonsense).
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On the Origin of the Genetic Code
Journal of Theoretical Biology, 1992The main theories which have been suggested to explain the origin of genetic code organization are discussed. The coevolution theory, which considers the genetic code as a map of the biosynthetic relationships between amino acids, seems to be based on a mechanism that links it closely to certain stages of the origin of metabolism, which makes it ...
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Science, 2021
Making room in the genetic code allows the creation of designer proteins with new building ...
Delilah Jewel, Abhishek Chatterjee
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Making room in the genetic code allows the creation of designer proteins with new building ...
Delilah Jewel, Abhishek Chatterjee
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Phylogeny of genetic codes and punctuation codes within genetic codes
Biosystems, 2015Punctuation codons (starts, stops) delimit genes, reflect translation apparatus properties. Most codon reassignments involve punctuation. Here two complementary approaches classify natural genetic codes: (A) properties of amino acids assigned to codons (classical phylogeny), coding stops as X (A1, antitermination/suppressor tRNAs insert unknown ...
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Methods, 2005
A general method was recently developed that makes it possible to genetically encode unnatural amino acids (UAAs) with diverse physical, chemical or biological properties in Escherichia coli, yeast, and mammalian cells. Over 30 UAAs have been cotranslationally incorporated into proteins with high fidelity and efficiency by means of a unique codon and ...
Jianming Xie, Peter G. Schultz
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A general method was recently developed that makes it possible to genetically encode unnatural amino acids (UAAs) with diverse physical, chemical or biological properties in Escherichia coli, yeast, and mammalian cells. Over 30 UAAs have been cotranslationally incorporated into proteins with high fidelity and efficiency by means of a unique codon and ...
Jianming Xie, Peter G. Schultz
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Reliability in the genetic code
Journal of Theoretical Biology, 1979Abstract Base sequences of φ × 174 and MS2 viruses genomes and of some mRNAs (Coat protein fd virus, Rabbit B. Globin, Rat Growth Hormone and Human Chorionic, Somatomammotropin) show a preferential use of some amino-acid codons. Based on this observation the reliability of three non-degenerate codes are analyzed.
S. Alvarado +4 more
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
In December of 1966 the last nucleotide triplet in the genetic code has been assigned (Brenner et al., 1967 [1]) thus completing years of studies aimed at deciphering the nature of the relationship between the sequences of genes and proteins. The end product, the table of the genetic code, was a crowning achievement of the quest to unravel the basic ...
Maciej Szymanski, Jan Barciszewski
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In December of 1966 the last nucleotide triplet in the genetic code has been assigned (Brenner et al., 1967 [1]) thus completing years of studies aimed at deciphering the nature of the relationship between the sequences of genes and proteins. The end product, the table of the genetic code, was a crowning achievement of the quest to unravel the basic ...
Maciej Szymanski, Jan Barciszewski
openaire +3 more sources