Results 291 to 300 of about 931,040 (332)
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The Science of Nature, 1973
The origin of the genetic code is not merely an evolutionary juggling of codon assignments until some optimal configuration is achieved. It is, rather, the more interesting and profound problem of how codon assignments arose. This is part and parcel of the origin of a translating mechanism.
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The origin of the genetic code is not merely an evolutionary juggling of codon assignments until some optimal configuration is achieved. It is, rather, the more interesting and profound problem of how codon assignments arose. This is part and parcel of the origin of a translating mechanism.
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Trends in Genetics, 2004
More than 30 novel amino acids have been genetically encoded in response to unique triplet and quadruplet codons including fluorescent, photoreactive and redox active amino acids, glycosylated and heavy atom derived amino acids in addition to those with keto, azido and acetylenic chains.
T. Ashton Cropp, Peter G. Schultz
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More than 30 novel amino acids have been genetically encoded in response to unique triplet and quadruplet codons including fluorescent, photoreactive and redox active amino acids, glycosylated and heavy atom derived amino acids in addition to those with keto, azido and acetylenic chains.
T. Ashton Cropp, Peter G. Schultz
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, 1980 When Beadle put forward the one gene: one enzyme hypothesis in 1945, he proposed that the function of each gene was to control the specificity of a single enzyme. With the genetic material, and thus the gene, identified as DNA the next problem to solve was the relationship between gene and enzyme or DNA and protein.
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Genetics: Clues in the code [PDF]
Nature, 2016 Gene exploration is providing unexpected insights into inflammatory bowel disease, and getting scientists closer to finding treatments that target the biological mechanisms.
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The genetic code and cyclic codes.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1983We proposed previously a cyclic code made of 22 triplets, which we now call the AB code. It is made up of the following chain: AUGGUGCCAUUCAAGACUAUGA. The letters A, U, C, G represent the classical symbols of the (purine and pyrimidine) bases of the genetic code.
J, Demongeot, J, Besson
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Stereospecificity of the genetic code
Journal of Molecular Evolution, 1974A sterical correlation of the amino acids to their anticodon nucleotides is given. The main principle is the intercalation of the amino acid and the binding of the aliphatic amino acid hydrogen atoms through hydrogen bonds to the π-electrons of the bases.
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1991
Most structural genes act by specifying the primary structures of specific protein molecules and, since the only difference between one gene and another lies in their nucleotide sequences, it follows that the particular nucleotide sequence of a gene must determine the amino acid sequence of the protein encoded by that gene.
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Most structural genes act by specifying the primary structures of specific protein molecules and, since the only difference between one gene and another lies in their nucleotide sequences, it follows that the particular nucleotide sequence of a gene must determine the amino acid sequence of the protein encoded by that gene.
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Optimization and the genetic code
Origins of life and evolution of the biosphere, 1989The present paper will focus on the relation between the structure of the table of the genetic code and the evolution of primitive organisms: it will be shown that the organization of the code table according to an optimization principle based on the notion of resistance to errors can provide a criterium for selection. The ordered aspect of the genetic
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Collinearity and the genetic code
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966Modern knowledge of the mechanism of expression of genes derives from the idea, formulated by Beadle in 1945, that each gene determines the structure of a specific protein At that time, this was all that could be said since very little was known about the chemical structure of genes and proteins and nothing about their synthesis Although ...
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2010
The next problem is the connection between information and function: How does DNA direct protein synthesis? The basic idea is straightforward and was indicated in Fig.2.2: The information is written in the DNA linearly; it is read and transferred to the assembler. Proteins are involved in reading, selecting, and assembling.
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The next problem is the connection between information and function: How does DNA direct protein synthesis? The basic idea is straightforward and was indicated in Fig.2.2: The information is written in the DNA linearly; it is read and transferred to the assembler. Proteins are involved in reading, selecting, and assembling.
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