Results 191 to 200 of about 4,570,239 (335)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Development of Cells Repository of <i>Betta</i> Species: A Tool for Genetic Conservation and Biotechnological Advancement. [PDF]

Animals (Basel)
Prukudom S, Piyasanti Y, Poungcharean S, Chaipipat S, Sritabtim K, Jurutha J, Phan-Poe C, Sinsiri R, Sirisuay S, Siripattarapravat K.   +9 more
europepmc   +1 more source

Genetic Polymorphism of β-Casein Gene in Polish Red Cattle-Preliminary Study of A1 and A2 Frequency in Genetic Conservation Herd. [PDF]

Animals (Basel), 2019
Cieślińska A, Fiedorowicz E, Zwierzchowski G, Kordulewska N, Jarmołowska B, Kostyra E.   +5 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

The Central-Periphery Hypothesis Revisited: Implications for Long-Term Genetic Conservation. [PDF]

Plants (Basel)
Verbylaitė R, Aravanopoulos FA, Baliuckas V, Tourvas N, Farsakoglou AM, Kotina VM, Lyrou FG, Juškauskaitė A, Petrokas R, Lygis V.   +9 more
europepmc   +1 more source

Gender, Local Knowledge, and Lessons Learnt in Documenting and Conserving Agrobiodiversity [PDF]

gender, biodiversity, agrobiodiversity, indigenous knowledge, conservation, sustainable management ...
Lambrou, Yianna, Laub, Regina
core  

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

Advanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner, Geo Jacob, Florian Raddatz, Gerko Wende   +3 more
wiley   +1 more source

The FORGENIUS Genomic Resources: New Genotyping Tools and Genomic Data for 23 Forest Tree Species and Their Genetic Conservation Units. [PDF]

Mol Ecol Resour
Pinosio S, Bagnoli F, Avanzi C, Castellani MB, Frascella A, McEvoy SL, Olsson S, Spanu I, Vajana E, FORGENIUS Consortium, González-Martínez SC, Pyhäjärvi T, Scotti I, Vendramin GG, Piotti A.   +14 more
europepmc   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

The role of Cacao agroforests in the genetic conservation of Cariniana legalis, an emblematic species of the atlantic forest. [PDF]

BMC Ecol Evol
Santos AS, Leal JB, Corrêa RX, Gramacho KP, Gaiotto FA.   +4 more
europepmc   +1 more source