Results 41 to 50 of about 3,375,405 (349)

Post-warming quality of goat oocytes under heat shock stress: A study of the maturation rate, heat shock protein-70, adenosine triphosphate, and glutathione levels [PDF]

Veterinary World
Background and Aim: Indonesia’s indigenous Kacang goat population is in decline, posing a threat to food security and genetic diversity. In vitro maturation and cryopreservation techniques are key strategies for genetic conservation.
Widjiati Widjiati, Ninik Darsini, Viski Fitri Hendrawan, Sultan Fadhilla Taqwa, Zahra Shabira, Devia Yoanita Kurniawati   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The European Commission’s regulatory proposal on new genomic techniques in plants: a focus on equivalence, complexity, and artificial intelligence

Environmental Sciences Europe
The European Commission has proposed to amend the EU GMO regulation, exempting certain genetically modified plants generated with new genomic techniques (NGTs) from risk assessment.
Juliane Mundorf, Samson Simon, Margret Engelhard   +2 more
doaj   +1 more source

Perspectives of genomics for genetic conservation of livestock [PDF]

, 2010
Genomics provides new opportunities for conservation genetics. Conservation genetics in livestock is based on estimating diversity by pedigree relatedness and managing diversity by choosing those animals that maximize genetic diversity.
Windig, J.J., Engelsma, K.A.
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification and validation of reference genes for quantitative real-time PCR in Corydalis saxicola under various abiotic stresses

Scientific Reports
Quantitative real-time PCR (qRT-PCR) is a commonly used method for measuring gene expression, but its accuracy depends on the use of stable reference genes for data normalization.
Liang Kang, Zhaodi Wen, Han Liu, Ying Lu, Mei Qin, Lirong Huang, Ming Lei, Cui Li, Dan Zhu, Li Li, Zhanjiang Zhang   +10 more
doaj   +1 more source

Conservation Genetics of the Cheetah: Genetic History and Implications for Conservation

, 2018
From allozymes in 1983 to whole genomes in 2015, genetic studies of the cheetah have been extensive. In this chapter we provide an overview of the available literature. Overall, patterns of genetic variation provided evidence of low variability and suggest this loss occurred thousands of years ago.
Schmidt-Küntzel, Anne, Dalton, Desiré L., Menotti-Raymond, Marilyn, Fabiano, Ezequiel, Charruau, Pauline, Johnson, Warren E., Sommer, Simone, Marker, Laurie, Kotzé, Antoinette, O’Brien, Stephen J.   +9 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

First Induced Mutant Population for Drought Tolerance in Vicia faba L.: Yield Traits and Stress Indices Across Generations and Water Regimes

Agronomy
Drought is a critical constraint for legume production in semi-arid regions, yet breeding for drought tolerance in faba bean through induced mutagenesis remains largely unexplored. To our knowledge, this is the first EMS-derived mutant population in faba
Oumaima Chetto, Loubna Belqadi, Ahmed Douaik, Etienne Bucher, Sarah Ouardy, Khalid Azim, Mohamed El Fechtali, Chaimae El Khnissi, Keny Karl Mounguele, Abdelghani Nabloussi   +9 more
doaj   +1 more source