Results 41 to 50 of about 269,589 (261)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evolution of Foamy Viruses: The Most Ancient of All Retroviruses

Viruses, 2013
Recent evidence indicates that foamy viruses (FVs) are the oldest retroviruses (RVs) that we know and coevolved with their hosts for several hundred million years. This coevolution may have contributed to the non-pathogenicity of FVs, an important factor
Jochen Bodem, Axel Rethwilm
doaj   +1 more source

Conservation Genetics, Precision Conservation, and De‐extinction [PDF]

Hastings Center Report, 2017
AbstractIt has been estimated that three species on the planet now go extinct every hour and that this rate is orders of magnitude higher than the planet has seen in previous catastrophic extinction events. We clearly are in the midst of a sixth extinction, and this one is different from the previous five. Why?
Rob, Desalle, George, Amato
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Enhancement of germination potential in lemon basil (Ocimum africanum Lour.) seeds using radiofrequency cold plasma treatment with oxygen, argon, and their combination

BMC Plant Biology
Background A rapid, cost-effective, and eco-friendly method was investigated to enhance the germination potential of lemon basil (Ocimum africanum Lour.) seeds using radiofrequency (RF) cold plasma treatment, addressing poor germination due to seed ...
Ram Kishor, Shivani Chandra, Vagmi Singh, Rakesh Kumar, Priyanka Prasad, Rajesh Singh, Nashra Aftab, Akancha Gupta, Himanshu Kumar Kushwaha, Parul Sharma, Birendra Kumar   +10 more
doaj   +1 more source

Effects of Polymorphism of the Growth Hormone Receptor (GHR) Gene on the Longevity and Milk Performance of White-Backed Cattle

Animals
Longevity is a trait influenced by numerous factors, including environmental factors, animal health, and productivity, which translate into economic considerations. In addition to many others, genetic factors are also very important.
Karolina Kasprzak-Filipek, Paweł Żółkiewski, Witold Chabuz, Wioletta Sawicka-Zugaj   +3 more
doaj   +1 more source

Parâmetros genéticos e ganhos na seleção em teste de progênies de polinização aberta de Eucalyptus pellita, Batatais–SP. Genetic parameters and gains with the selection in open pollinated progeny test of Eucalyptus pellita, in Batatais–SP. [PDF]

Revista do Instituto Florestal, 2010
Os objetivos deste estudo foram estimar parâmetros genéticos, ganhos naseleção e avaliar o desenvolvimento silvicultural da espécie em um teste de progênies de Eucalyptus pellita, aos 23 anos de idade, estabelecido em Batatais, SP.
Marcelo ZANATA, Miguel Luiz Menezes FREITAS, Morgana Tramontini SILVA, Eurípedes MORAIS, Antonio Carlos Scatena ZANATTO, Alexandre Magno SEBBENN   +5 more
doaj  

Genetic variation in subdivided populations and conservation genetics [PDF]

Heredity, 1986
The genetic differentiation of populations is usually studied by using the equilibrium theory of Wright's infinite island model. In practice, however, populations are not always in equilibrium, and the number of subpopulations is often very small.
S L, Varvio, R, Chakraborty, M, Nei
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source