Results 71 to 80 of about 3,375,405 (349)

Profiles and roles of N6-methyladenosine modification in bovine oocyte maturation

BMC Genomics
Background Bovine oocyte quality is crucial for successful in vitro embryo production; therefore, elucidating the mechanisms underlying oocyte maturation is essential.
Tiancang Han, Zhichao Wang, Xinqi Gan, Zhiyuan Yang, Wenzhuo Wang, Kunlong Hu, Ruiqing Zhu, Yunsheng Li, Yunhai Zhang, Zubing Cao   +9 more
doaj   +1 more source

Differentiation measures for conservation genetics [PDF]

Evolutionary Applications, 2018
AbstractWe compare the two main classes of measures of population structure in genetics: (i) fixation measures such as FST, GST, and θ and (ii) allelic differentiation measures such as Jost's D and entropy differentiation. These two groups of measures quantify complementary aspects of population structure, which have no necessary relationship with each
Lou Jost, Frederick Archer, Sarah Flanagan, Oscar Gaggiotti, Sean Hoban, Emily Latch   +5 more
openaire   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Shotgun Sequencing for Microsatellite Identification in Ilex paraguariensis (Aquifoliaceae)

Applications in Plant Sciences, 2013
Premise of the study: Ilex paraguariensis is a native tree species from Brazil, Argentina, and Paraguay that is used in the production of beverages, medicines, and cosmetics.
Marlei F. Pereira, Ana Y. Ciampi, Peter W. Inglis, Valderês A. Souza, Vânia C. R. Azevedo   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Genetic control of wood quality of Myracrodruon urundeuva populations under anthropogenic disturbance

Crop Breeding and Applied Biotechnology, 2020
Forest fragmentation in the Cerrado biome exposes the tree species Myracrodruon urundeuva to the risk of extinction. Thus, the objective of the study was to evaluate silvicultural characteristics related to wood quality, based on genetic parameters ...
Lara Comar Riva, Marcela Aparecida de Moraes, José Cambuim, Daniele Fernanda Zulian, Luciane Missae Sato, Francieli Alves Caldeira, Alan Rodrigo Panosso, Mario Luiz Teixeira de Moraes   +7 more
doaj  

Genetic diversity of Piracanjuba populations in fish stocking programs in the Tietê River, Brazil

Revista Colombiana de Ciencias Pecuarias, 2019
Background: Piracanjuba (Brycon orbignyanus) is a fish species highly affected by anthropogenic actions such as overfishing, water pollution, and hydroelectric developments. This species is currently considered in danger of extinction.
Nelson M. Lopera-Barrero, Silvio C. A. Santos, Pedro L. Castro, Felipe P. Souza, Angela R. Poveda-Parra, Victor C. F. Pandolfi, Andrei L. Yamachita, Angela M. Urrea-Rojas, Diego A. Rojas-Meza, Ricardo P. Ribeiro   +9 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source