Results 71 to 80 of about 4,605,118 (350)

A general framework for estimating the relative pathogenicity of human genetic variants

Nature Genetics, 2014
Current methods for annotating and interpreting human genetic variation tend to exploit a single information type (for example, conservation) and/or are restricted in scope (for example, to missense changes).
Martin Kircher, Daniela M. Witten, Preti Jain, B. O’Roak, G. Cooper, J. Shendure   +5 more
semanticscholar   +1 more source

Resource conservation manifests in the genetic code

Science, 2020
Maximizing elements for your genome The accumulation of mutations is typically limited by selective parameters. One such parameter is the elements needed to build proteins and molecules to maintain cells.
L. Shenhav, D. Zeevi
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Enhancement of germination potential in lemon basil (Ocimum africanum Lour.) seeds using radiofrequency cold plasma treatment with oxygen, argon, and their combination

BMC Plant Biology
Background A rapid, cost-effective, and eco-friendly method was investigated to enhance the germination potential of lemon basil (Ocimum africanum Lour.) seeds using radiofrequency (RF) cold plasma treatment, addressing poor germination due to seed ...
Ram Kishor, Shivani Chandra, Vagmi Singh, Rakesh Kumar, Priyanka Prasad, Rajesh Singh, Nashra Aftab, Akancha Gupta, Himanshu Kumar Kushwaha, Parul Sharma, Birendra Kumar   +10 more
doaj   +1 more source

Plant Conservation Biology: a view from the Mediterranean ecoregions

Mediterranean Botany, 2021
This Special Issue provides an overview of the current status of plant conservation biology in Spain and other regions around the World. Papers represent selected outstanding presentations made during the 9th Congress of the Spanish Society of Plant ...
Antonio Jesús Mendoza-Fernández, Esteban Salmerón-Sánchez, Juan Lorite, Juan Francisco Mota, Julio Peñas   +4 more
doaj   +1 more source

Genetic variation in subdivided populations and conservation genetics [PDF]

Heredity, 1986
The genetic differentiation of populations is usually studied by using the equilibrium theory of Wright's infinite island model. In practice, however, populations are not always in equilibrium, and the number of subpopulations is often very small.
S L, Varvio, R, Chakraborty, M, Nei
openaire   +2 more sources

Comparing RADseq and microsatellites for estimating genetic diversity and relatedness — Implications for brown trout conservation

Ecology and Evolution, 2019
The conservation and management of endangered species requires information on their genetic diversity, relatedness and population structure. The main genetic markers applied for these questions are microsatellites and single nucleotide polymorphisms ...
A. Lemopoulos, J. Prokkola, S. Uusi‐Heikkilä, A. Vasemägi, A. Huusko, P. Hyvärinen, M. Koljonen, J. Koskiniemi, A. Vainikka   +8 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Profiles and roles of N6-methyladenosine modification in bovine oocyte maturation

BMC Genomics
Background Bovine oocyte quality is crucial for successful in vitro embryo production; therefore, elucidating the mechanisms underlying oocyte maturation is essential.
Tiancang Han, Zhichao Wang, Xinqi Gan, Zhiyuan Yang, Wenzhuo Wang, Kunlong Hu, Ruiqing Zhu, Yunsheng Li, Yunhai Zhang, Zubing Cao   +9 more
doaj   +1 more source

The management of tree genetic resources and the livelihoods of rural communities in the tropics: non-timber forest products, smallholder agroforestry practices and tree commodity crops [PDF]

, 2015
Products and services provided by trees in forests and farmland support the needs and promote the wellbeing of hundreds of millions of people in the tropics.
Clement, C.R., Cornelius, J.P., Dawson, Ian K., Jamnadass, Ramni H., Kalinganire, A., Leakey, R., Masters, E., Roshetko, James M., Tchoundjeu, Z., Vinceti, B., Weber, John C.   +10 more
core   +1 more source