Results 181 to 190 of about 7,428,370 (340)

Participation bias in the estimation of heritability and genetic correlation. [PDF]

Proc Natl Acad Sci U S A
Song S, Benonisdottir S, Liu JS, Kong A.
europepmc   +1 more source

The evolution of dimorphic traits: predicting the genetic correlation between environments. [PDF]

, 1994
Derek A. Roff
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Changes in genetic correlations by index selection [PDF]

Genetics Selection Evolution, 1991
openaire   +4 more sources

Linear Heritability and Genetic Correlation Estimates

, 1972
Yukio Yamada
openalex   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Disentangling horizontal and vertical Pleiotropy in genetic correlation estimation: introducing the HVP model. [PDF]

Hum Genet
Amente LD, Mills NT, Le TD, Hyppönen E, Lee SH.   +4 more
europepmc   +1 more source

Phenotypic plasticity in Crepis tectorum (Asteraceae): genetic correlations across light regimens [PDF]

, 1994
Stefan Andersson, Ruth G. Shaw
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Transethnic genetic correlation estimates from summary statistics

bioRxiv, 2016
Brielin C. Brown, Chun Jimmie Ye, A. Price, N. Zaitlen   +3 more
semanticscholar   +1 more source