Results 201 to 210 of about 974,406 (246)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis. [PDF]

Transl Vis Sci Technol
Lei S, Liu Y.
europepmc   +1 more source

Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization. [PDF]

Sci Rep
Ding L, Chen B, Zhou Z, Mei Z, Cao K, Lu X, Chen W.   +6 more
europepmc   +1 more source

Association between 25(OH) vitamin D and schizophrenia: shared genetic correlation, pleiotropy, and causality. [PDF]

Front Nutr
Rong GW, Li XM, Lu HM, Su MZ, Jin Y.
europepmc   +1 more source

Local genetic correlation via knockoffs reduces confounding due to cross-trait assortative mating. [PDF]

Am J Hum Genet
Ma S, Wang F, Border R, Buxbaum J, Zaitlen N, Ionita-Laza I.   +5 more
europepmc   +1 more source

Leisure-Time Physical Activity, Sedentary Behavior, and Biological Aging: Evidence From Genetic Correlation and Mendelian Randomization Analyses. [PDF]

Scand J Med Sci Sports
Zhao X, Wu X, He L, Xiao J, Xiang R, Sha L, Tang M, Hao Y, Qu Y, Xiao C, Qin C, Hou J, Deng Q, Zhu J, Zheng S, Zhou J, Yu T, Yang B, Song X, Han T, Liao J, Zhang T, Fan M, Li J, Jiang X.   +24 more
europepmc   +1 more source

Ankylosing spondylitis and the genetic correlation of extra-articular manifestations: Evidence from bidirectional Mendelian randomization and Bayesian colocalization. [PDF]

Medicine (Baltimore)
Pan H, Ye Y, Wang D, Zheng J, Zhao Z, Zhao K.   +5 more
europepmc   +1 more source