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Genetic correlates of efavirenz hypersusceptibility
AIDS, 2004Non-nucleoside reverse transcriptase inhibitor (NNRTI) hypersusceptibility is seen in approximately 30% of HIV isolates with nucleoside reverse transcriptase inhibitor (NRTI) resistance. NNRTI hypersusceptibility has been associated with improved outcomes to NNRTI-based therapy.To determine the genetic correlates of efavirenz hypersusceptibility.Paired
Nancy S, Shulman +4 more
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Genetic correlates of insight in schizophrenia
Schizophrenia Research, 2018Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight.Schizophrenia case-only analysis of the Clinical Antipsychotics ...
Rose Mary Xavier +3 more
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The Genetic Correlation Between Procrastination and Impulsivity
Twin Research and Human Genetics, 2014The reported genetic correlation of 1.0 between the traits of procrastination and impulsivity (Gustavson, D. E., Miyake, A., Hewitt, J. K., & Friedman, N. P. (2014). Psychological Science), which was held to support an evolutionary origin of the relationship between the two traits, was tested in data from two large samples of twins from Australia ...
Loehlin, John C., Martin, Nicholas G.
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Oligodendrogliomas: clinical and genetic correlations
Current Opinion in Neurology, 2001Oligodendrogliomas, once obscure, are now recognized as a relatively common form of primary brain tumour, and are among the most chemosensitive of all solid human malignancies. New histopathological, molecular, and genetic information has, for the first time, allowed the distinction of several subtypes of human glioma with predictable biological and ...
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A TEST OF THE HYPOTHESIS THAT CORRELATIONAL SELECTION GENERATES GENETIC CORRELATIONS
Evolution, 2012Theory predicts that correlational selection on two traits will cause the major axis of the bivariate G matrix to orient itself in the same direction as the correlational selection gradient. Two testable predictions follow from this: for a given pair of traits, (1) the sign of correlational selection gradient should be the same as that of the genetic ...
Derek A, Roff, Daphne J, Fairbairn
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Inference about genetic correlations
Behavior Genetics, 1988In polygenic systems genetic correlations and the factors and specific genetic variances from genetic correlation matrices are often interpreted in terms of sets of genes common or specific to variables. While these inferences may indeed be true, a genetic correlation is not always sufficient evidence for the inferences.
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Genetic Correlations with Multiple Alleles
Biometrics, 1960Hogben [1932] gave the values for filial and fraternal correlations for matings involving two alleles in a panmictic population. The subject has been considered in great detail by Li [1955], but the known results are restricted to the case of two alleles. Consequently, if it is desired to compare a correlation derived from actual experimental data with
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1997
The last chapter examined the genetic basis of the resemblance between parents and offspring for a single trait. However, it is common experience that traits are not inherited as independent units, but that several traits tend to be associated with each other.
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The last chapter examined the genetic basis of the resemblance between parents and offspring for a single trait. However, it is common experience that traits are not inherited as independent units, but that several traits tend to be associated with each other.
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The effect of simultaneous selection on the genetic correlation
Theoretical and Applied Genetics, 1995The theoretical effect of simultaneous selection on the genetic correlations between two traits over 20 generations was examined using simulation. For each generation, a population of 50 male and 50 female diploid gen otypes with 15 loci, each with two alleles, was synthesized. None of the loci exhibited dominance.
I, McMillan +3 more
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Genetic Correlates of Adult Attachment Style
Personality and Social Psychology Bulletin, 2008Attachment theory attempts to explain effects of social experiences, not genes, on personality development. Most studies of the development of attachment insecurities support this emphasis on social experiences rather than genes, although there are exceptions.
Omri, Gillath +3 more
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