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Are Genetic Correlations and Environmental Correlations Correlated?
Nature, 1970CORRELATIONS between different characters measured on individuals of a population have both genetic and environmental causes. In an extensive genetic analysis of the open-field behaviour of mice, which is a widely used index of “emotionality”, we have found that genetic and corresponding environmental patterns of association among pairs of characters ...
Hegmann, J P, Fries, J C
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Genetic correlation in otosclerosis
American Journal of Otolaryngology, 1999The aim of this study was to determine the relationship of HLA typing in patients with otosclerosis.We used a prospective study in which HLA typing of 100 surgically confirmed otosclerosis patients were compared with age and sex matched normal individuals.HLA-A3, HLA-A9, HLA-A11, and HLA-B13 were found to be significantly higher (P < .05, .01, and .01,
S K, Singhal +4 more
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Estimating genetic correlations
Annals of Human Genetics, 1980A method is proposed for simultaneous estimation of genetical variance and covariance components for quantitative characters and hence correlations and cross-correlations between relatives. It proceeds by successive approximations, which are not difficult to compute. Judging by examples, they appear to converge rapidly in practice.
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Genetic correlates of insight in schizophrenia
Schizophrenia Research, 2018Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight.Schizophrenia case-only analysis of the Clinical Antipsychotics ...
Rose Mary Xavier +3 more
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Genetic correlates of efavirenz hypersusceptibility
AIDS, 2004Non-nucleoside reverse transcriptase inhibitor (NNRTI) hypersusceptibility is seen in approximately 30% of HIV isolates with nucleoside reverse transcriptase inhibitor (NRTI) resistance. NNRTI hypersusceptibility has been associated with improved outcomes to NNRTI-based therapy.To determine the genetic correlates of efavirenz hypersusceptibility.Paired
Nancy S, Shulman +4 more
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Genetic correlations in validating emotionality
Behavior Genetics, 1990Sixty-six rats of seven inbred strains were observed in an open field (OF) and in a light-dark preference box (LDB). Each set of apparatus provides measures of locomotor activity and of the time spent in the "most protected" area (the corners in the OF, the dark compartment in the LDB). These measures are proposed to be indices of emotionality.
F J, van der Staay +2 more
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The Genetic Correlation Between Procrastination and Impulsivity
Twin Research and Human Genetics, 2014The reported genetic correlation of 1.0 between the traits of procrastination and impulsivity (Gustavson, D. E., Miyake, A., Hewitt, J. K., & Friedman, N. P. (2014). Psychological Science), which was held to support an evolutionary origin of the relationship between the two traits, was tested in data from two large samples of twins from Australia ...
Loehlin, John C., Martin, Nicholas G.
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Inference about genetic correlations
Behavior Genetics, 1988In polygenic systems genetic correlations and the factors and specific genetic variances from genetic correlation matrices are often interpreted in terms of sets of genes common or specific to variables. While these inferences may indeed be true, a genetic correlation is not always sufficient evidence for the inferences.
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A TEST OF THE HYPOTHESIS THAT CORRELATIONAL SELECTION GENERATES GENETIC CORRELATIONS
Evolution, 2012Theory predicts that correlational selection on two traits will cause the major axis of the bivariate G matrix to orient itself in the same direction as the correlational selection gradient. Two testable predictions follow from this: for a given pair of traits, (1) the sign of correlational selection gradient should be the same as that of the genetic ...
Derek A, Roff, Daphne J, Fairbairn
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Genetic Correlations with Multiple Alleles
Biometrics, 1960Hogben [1932] gave the values for filial and fraternal correlations for matings involving two alleles in a panmictic population. The subject has been considered in great detail by Li [1955], but the known results are restricted to the case of two alleles. Consequently, if it is desired to compare a correlation derived from actual experimental data with
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