Results 231 to 240 of about 1,946,419 (298)

Genetic correlation and causation of craniofacial microsomia with 33 diseases in Asian populations: insights from large-scale genome-wide cross-trait analysis. [PDF]

Sci Rep
Luo P, Zhao S, Zhang Z, Guo R, Zhang Q.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Blood Pressure, Cardiometabolic Traits, and Cardiovascular Events in Women With Uterine Fibroids: A Genetic Correlation and Mendelian Randomization Study. [PDF]

J Am Heart Assoc
Henry J, Berrandou T, Brewster LM, Bouatia-Naji N.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Accelerating Heritability, Genetic Correlation, and Genome-Wide Association Imaging Genetic Analyses in Complex Pedigrees. [PDF]

Hum Brain Mapp
Donohue B, Gao S, Nichols TE, Adhikari BM, Ma Y, Jahanshad N, Thompson PM, McMahon FJ, Humphries EM, Burroughs W, Ament SA, Mitchell BD, Ma T, Chen S, Medland SE, Blangero J, Hong LE, Kochunov P.   +17 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Causal associations of interleukins and osteoporosis: A genetic correlation study. [PDF]

Medicine (Baltimore)
Chen H, Lin H, Dai J.
europepmc   +1 more source

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis. [PDF]

Transl Vis Sci Technol
Lei S, Liu Y.
europepmc   +1 more source

Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization. [PDF]

Sci Rep
Ding L, Chen B, Zhou Z, Mei Z, Cao K, Lu X, Chen W.   +6 more
europepmc   +1 more source

Association between 25(OH) vitamin D and schizophrenia: shared genetic correlation, pleiotropy, and causality. [PDF]

Front Nutr
Rong GW, Li XM, Lu HM, Su MZ, Jin Y.
europepmc   +1 more source