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Inference about genetic correlations
Behavior Genetics, 1988In polygenic systems genetic correlations and the factors and specific genetic variances from genetic correlation matrices are often interpreted in terms of sets of genes common or specific to variables. While these inferences may indeed be true, a genetic correlation is not always sufficient evidence for the inferences.
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Genetic Correlates of Adult Attachment Style
Personality and Social Psychology Bulletin, 2008Attachment theory attempts to explain effects of social experiences, not genes, on personality development. Most studies of the development of attachment insecurities support this emphasis on social experiences rather than genes, although there are exceptions.
Omri, Gillath +3 more
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Genetic correlations with ethanol withdrawal severity
Pharmacology Biochemistry and Behavior, 1983A major goal of pharmacogenetic research on alcoholism remains the identification of some "marker" that could predict the liability of a particular individual for a genetic susceptibility to develop alcoholism. The present paper presents evidence that the severity of withdrawal from physical dependence on ethanol varies widely among inbred strains of ...
J C, Crabbe, E R, Young, A, Kosobud
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Genetic correlates of insight in schizophrenia
Schizophrenia Research, 2018Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight.Schizophrenia case-only analysis of the Clinical Antipsychotics ...
Rose Mary Xavier +3 more
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Oligodendrogliomas: clinical and genetic correlations
Current Opinion in Neurology, 2001Oligodendrogliomas, once obscure, are now recognized as a relatively common form of primary brain tumour, and are among the most chemosensitive of all solid human malignancies. New histopathological, molecular, and genetic information has, for the first time, allowed the distinction of several subtypes of human glioma with predictable biological and ...
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Genetic Correlations with Multiple Alleles
Biometrics, 1960Hogben [1932] gave the values for filial and fraternal correlations for matings involving two alleles in a panmictic population. The subject has been considered in great detail by Li [1955], but the known results are restricted to the case of two alleles. Consequently, if it is desired to compare a correlation derived from actual experimental data with
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ESTABLISHING GENETIC CORRELATIONS INVOLVING PARASITE VIRULENCE
Evolution, 1998For many host-parasite interactions, virulence is necessarily affected by population densities, transmission biology of the parasite, and proliferation of the parasite at the expense of its host. Attempts to experimentally demonstrate genetic correlations involving virulence therefore need to employ protocols controlling for variation in the number of ...
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Estimating genetic correlations from inbred strains
Behavior Genetics, 1981Genetic correlations measure the extent of pleiotropic effects of polygenes on pairs of characters or the closeness of linkage between sets of loci influencing the traits and held in allelic (gametic) disequilibrium. Their importance for research lies primarily in predicting correlated responses of one trait to selection based on values for another ...
J P, Hegmann, B, Possidente
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1997
The last chapter examined the genetic basis of the resemblance between parents and offspring for a single trait. However, it is common experience that traits are not inherited as independent units, but that several traits tend to be associated with each other.
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The last chapter examined the genetic basis of the resemblance between parents and offspring for a single trait. However, it is common experience that traits are not inherited as independent units, but that several traits tend to be associated with each other.
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Nonrandom Sampling in Human Genetics: Familial Correlations
Mathematical Medicine and Biology, 1984In the context of human genetics, sampling is often nonrandom in that pedigrees are frequently selected by virtue of their having at least one affected individual. For quantitative traits, it may be that the proband is selected because of a phenotypic value above some predetermined cut-point; this will also be true for diseases defined by a cut-point ...
Hanis, Craig L., Chakraborty, Ranajit
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