Results 261 to 270 of about 7,428,370 (340)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization. [PDF]

Sci Rep
Ding L, Chen B, Zhou Z, Mei Z, Cao K, Lu X, Chen W.   +6 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Association between 25(OH) vitamin D and schizophrenia: shared genetic correlation, pleiotropy, and causality. [PDF]

Front Nutr
Rong GW, Li XM, Lu HM, Su MZ, Jin Y.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Variance of genetic reducing sugars and dry matter and their correlations with agronomic traits in potatoes [PDF]

, 2000
Adriana Tourinho Salamoni, A. da S. Pereira, Judith Viégas, Ângela Diniz Campos, Carla Simone De Almeida Chalá   +4 more
openalex   +1 more source

Heritability and Genetic Correlation of Age at First Egg and Egg Number up to 40 Weeks of Age After Long-Term Selection in Taiwan Indigenous Chicken. [PDF]

Animals (Basel)
Lin DY, Chu CT, Lin MY, Tsai MY, Tzeng SJ, Wu MC, Chang HL.   +6 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Ankylosing spondylitis and the genetic correlation of extra-articular manifestations: Evidence from bidirectional Mendelian randomization and Bayesian colocalization. [PDF]

Medicine (Baltimore)
Pan H, Ye Y, Wang D, Zheng J, Zhao Z, Zhao K.   +5 more
europepmc   +1 more source