Results 101 to 110 of about 7,495,262 (331)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Effects of cell cycle noise on excitable gene circuits [PDF]

, 2016
We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect ...
Bennett, Matthew R., Gupta, Chinmaya, Josić, Krešimir, Ott, William, Veliz-Cuba, Alan   +4 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Assessing Multivariate Constraints to Evolution across Ten Long-Term Avian Studies [PDF]

, 2014
Background In a rapidly changing world, it is of fundamental importance to understand processes constraining or facilitating adaptation through microevolution.
Balbontín, Javier, Burke, Terry A, Charmantier, Anne, de Lope, Florentino, Doutrelant, Claire, Gregoire, Arnaud, Gustafsson, Lars, Hansson, Bengt,, Hasselquist, Dennis,, Lund University., Lund University., Lund University., Lund University., Marzal, Alfonso, Mills, James A, Møller, Anders P, Nakagawa, Shinichi, Tarka, Maja,, Teplitsky, Celine, Wheelwright, Nathaniel T, Yarrall, John W   +20 more
core   +6 more sources

Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies

bioRxiv, 2016
Large-scale genome-wide association results are typically obtained from a fixed-effects meta-analysis of GWAS summary statistics from multiple studies spanning different regions and/or time periods. This approach averages the estimated effects of genetic
R. Vlaming, A. Okbay, C. A. Rietveld, M. Johannesson, P. Magnusson, A. Uitterlinden, A. Uitterlinden, F. V. Rooij, A. Hofman, A. Hofman, A. Hofman, Patrick J. F. Groenen, Patrick J. F. Groenen, Roy Thurik, P. Koellinger   +14 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phenotypic and genetic parameters of milk yield traits in first-calf heifers of Holstein-Friesian breed

Mljekarstvo, 2020
The objective of this paper was to study variability, heritability and correlation of the three production traits in 1409 first-calf heifers of Holstein-Friesian breed; including the determination of the quantity of milk during lactation (ML), the ...
Mladen Popovac, Aleksandar Miletić, Nikola Raguž, Radmila Beskorovajni, Dragan Stanojević, Mihailo Radivojević, Nenad Mićić, Nenad Đurić   +7 more
doaj   +1 more source

Tissue Specificity and Sex-Specific Regulatory Variation Permit the Evolution of Sex-Biased Gene Expression [PDF]

, 2016
Genetic correlations between males and females are often thought to constrain the evolution of sexual dimorphism. However, sexually dimorphic traits and the underlying sexually dimorphic gene expression patterns are often rapidly evolving.
Dean, R, Mank, JE
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Smoking and caffeine consumption:a genetic analysis of their association [PDF]

, 2017
Smoking and caffeine consumption show a strong positive correlation, but the mechanism underlying this association is unclear. Explanations include shared genetic/environmental factors or causal effects.
Benowitz, Boker, Boyd, Brion, Bulik-Sullivan, Bulik-Sullivan, Cornelis, Davey Smith, Davey Smith, De Moor, Falconer, Ferdman, Fernandez, Fraser, Fredholm, Freedman, Gasior, Hettema, Hewlett, Hinds, Joeres, Jones, Kendler, Kiecolt, Langmann, McMahon, Nivard, Olsen, Palmer, Poelen, Posthuma, Rezvani, Shoaib, Sorlie, Swan, Swan, Swanson, TAG, Taylor, Thorgeirsson, Treur, Vink, Vink, Willemsen, Willemsen, Wray   +45 more
core   +2 more sources