This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Os objetivos neste trabalho foram comparar modelos animais alternativos para a análise do período de gestação e verificar se essa característica possui variabilidade genética suficiente para ser incluída em programas de seleção, por meio de estimativas ...
Talita Buttarello Mucari +3 more
doaj +1 more source
Developing selection indexes & estimation of genetic parameters for traits of economic importance in dairy cattle under once-a-day milking : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Animal Science, Institute of Veterinary, Animal Biomedical Sciences, Massey University, Palmerston North, New Zealand [PDF]
In New Zealand, about 5% of dairy herds are milked once-a-day (OAD). The cows are inseminated using sires from the twice-a-day milking system (TAD) evaluated on breeding worth (BW) or an OAD selection index.
Lembeye Illanes, Felipe
core
Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control [PDF]
Background Mental health disorders commonly co-occur, even between conceptually distinct syndromes, such as internalizing and externalizing disorders.
Ellingson, J. M +4 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The genetic parameters of growth traits in the New Zealand White rabbits kept at Sheep Breeding and Research Station, Sandynallah, The Nilgiris, India were estimated by partitioning the variance and covariance components.
M. Sakthivel +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Com os objetivos de estimar parâmetros genéticos e avaliar a tendência genética e a fenotípica para as características peso ao nascer (PN), ganho médio diário do nascimento à desmama (GMDND), peso à desmama ajustado para 205 dias (P205) e para os escores
Tomás Weber +5 more
doaj +1 more source
Genetic Covariance Structure of Reading, Intelligence and Memory in Children [PDF]
This study investigates the genetic relationship among reading performance, IQ, verbal and visuospatial working memory (WM) and short-term memory (STM) in a sample of 112, 9-year-old twin pairs and their older siblings.
A Baddeley +56 more
core +5 more sources
A COMPARISON OF GENETIC AND PHENOTYPIC CORRELATIONS [PDF]
Genetic variances and correlations lie at the center of quantitative evolutionary theory. They are often difficult to estimate, however, due to the large samples of related individuals that are required. I investigated the relationship of genetic- and phenotypic-correlation magnitudes and patterns in 41 pairs of matrices drawn from the literature in ...
openaire +2 more sources

