Results 281 to 290 of about 7,495,262 (331)

Drug-induced liver injury (DILI) ascribed to non-steroidal anti-inflammatory drugs (NSAIDs) in the USA-Update with genetic correlations. [PDF]

open access: yesLiver Int
Bonkovsky HL   +11 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source
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Genetic correlations between subcortical brain volumes and psychiatric disorders

British Journal of Psychiatry, 2020
Summary Psychiatric disorders as well as subcortical brain volumes are highly heritable. Large-scale genome-wide association studies (GWASs) for these traits have been performed. We investigated the genetic correlations between five psychiatric disorders
K. Ohi   +6 more
semanticscholar   +1 more source

Are Genetic Correlations and Environmental Correlations Correlated?

Nature, 1970
CORRELATIONS between different characters measured on individuals of a population have both genetic and environmental causes. In an extensive genetic analysis of the open-field behaviour of mice, which is a widely used index of “emotionality”, we have found that genetic and corresponding environmental patterns of association among pairs of characters ...
Hegmann, J P, Fries, J C
openaire   +2 more sources

Pediatric Leigh Syndrome: Neuroimaging Features and Genetic Correlations

Annals of Neurology, 2020
The neurodiagnostic criteria of Leigh syndrome have not yet been clearly redefined based on the expanding of molecular etiologies. We aimed to analyze 20 years of clinical, genetic, and magnetic resonance studies from our Leigh syndrome cohort to provide
C. Alves   +12 more
semanticscholar   +1 more source

Genetic correlations and ecological networks shape coevolving mutualisms.

Ecology Letters, 2020
Ecological interactions shape the evolution of multiple species traits in populations. These traits are often linked to each other through genetic correlations, affecting how each trait evolves through selection imposed by interacting partners.
A. P. Assis   +5 more
semanticscholar   +1 more source

Genetic correlation in otosclerosis

American Journal of Otolaryngology, 1999
The aim of this study was to determine the relationship of HLA typing in patients with otosclerosis.We used a prospective study in which HLA typing of 100 surgically confirmed otosclerosis patients were compared with age and sex matched normal individuals.HLA-A3, HLA-A9, HLA-A11, and HLA-B13 were found to be significantly higher (P < .05, .01, and .01,
S K, Singhal   +4 more
openaire   +2 more sources

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