Results 141 to 150 of about 3,055,534 (337)

Relevance of genetic counselling in couples prior to intracytoplasmic sperm injection [PDF]

, 1997
Hans‐Ulrich Pauer, B. Hinney, H. W. Michelmann, E. W. Krasemann, Barbara Zoll, Werner Engel   +5 more
openalex   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Duchenne muscular dystrophy and idiopathic hyperCKemia in a family causing confusion in genetic counselling [PDF]

, 1996
K. Bushby, Judith Goodship, Daisy Haggerty, A. Heald, Timothy J. Walls   +4 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Objectives of genetic counselling: differing views of purchasers, providers and users [PDF]

, 1998
Susan Michie, Abi Allanson, David Armstrong, John Weinman, Martin Bobrow, Theresa M. Marteau   +5 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

P551: Implementing next-generation sequencing as part of newborn screening in state public health laboratories: Status and barriers

Genetics in Medicine Open
Margaux Haiber, Christine Seymour, Kristen Sund, Holly Snyder   +3 more
doaj   +1 more source

Assisting Families through Genetic Counseling

, 1983
Adrianne K. Hamilton, Dorinda N. Noble
openalex   +1 more source

Genetic counseling follow-up - a retrospective study with a quantitative approach [PDF]

, 1999
João Monteiro de Pina Neto, Eucia Beatriz Lopes Petean   +1 more
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source