Results 81 to 90 of about 199,361 (374)
Recently, mutations have been identified in six genes (PIGA, PIGY, PIGO, PGAP2, PIGW and PGAP3) encoding proteins in the Glycosyl phosphatidylinositol(GPI)-anchor-synthesis pathway in individuals with hyperphosphatasia with impaired intellectual ...
Yijun Pan+3 more
doaj +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
Genetic counselors' scope of practice and challenges in genetic counseling services in Saudi Arabia [PDF]
Genetic counseling is an evolving field in Saudi Arabia. In 2015, genetic counseling was recognized as a Master's program by the Saudi Commission for Health Specialties.
Al-Zaidan, Hamad+2 more
core +1 more source
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
Parents' understanding about psychological well-being could affect their efforts in facing and accepting the children with thalassemia major. Genetic counseling and genetic screening are some attempts made to provide an understanding about this illness ...
Costrie G. Widayanti, Kartika Sari Dewi
doaj +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Speaker and Time-aware Joint Contextual Learning for Dialogue-act Classification in Counselling Conversations [PDF]
The onset of the COVID-19 pandemic has brought the mental health of people under risk. Social counselling has gained remarkable significance in this environment. Unlike general goal-oriented dialogues, a conversation between a patient and a therapist is considerably implicit, though the objective of the conversation is quite apparent.
arxiv
Alzheimer’s Prevention Initiative Generation Program: Development of an APOE genetic counseling and disclosure process in the context of clinical trials [PDF]
IntroductionAs the number of Alzheimer’s disease (AD) prevention studies grows, many individuals will need to learn their genetic and/or biomarker risk for the disease to determine trial eligibility.
Bradbury, Angela+10 more
core +1 more source
From genetic counseling to “genomic counseling” [PDF]
Genetic counseling is “the process of helping people understand and adapt to the medical, psychological, and familial implications of genetic contributions to disease.” Traditionally, this process includes collecting and interpreting the family and medical history, risk assessment, a comprehensive educational process for potential genetic testing ...
openaire +3 more sources
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source