Results 131 to 140 of about 2,863,419 (210)

Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging. [PDF]

Geroscience
Tanguay AP, Menon NG, Slavin E, Moody M, McEwen E, Jay GD, Lorenzo J, Bartley JM, Scanlon VM, Deymier AC, Schmidt TA.   +10 more
europepmc   +1 more source

Rankl genetic deficiency and functional blockade undermine skeletal stem and progenitor cell differentiation. [PDF]

Stem Cell Res Ther
Schiavone ML, Crisafulli L, Camisaschi C, De Simone G, Liberati FR, Palagano E, Rucci N, Ficara F, Sobacchi C.   +8 more
europepmc   +1 more source

Genetics of immunoglobulin a deficiency

, 2018
Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasian populations. It is defined as a serum IgA level below 0.07 g/L with normal IgM and IgG levels in an individual older than four years of age. Approximately one-third of these patients present with recurrent respiratory and gastrointestinal tract infections ...
openaire   +1 more source

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. [PDF]

Nat Commun, 2018
Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL.   +20 more
europepmc   +1 more source

Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death. [PDF]

JCI Insight, 2019
Calabrese DR, Wang P, Chong T, Hoover J, Singer JP, Torgerson D, Hays SR, Golden JA, Kukreja J, Dugger D, Christie JD, LTOG investigators, Greenland JR.   +12 more
europepmc   +1 more source

Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis. [PDF]

JCI Insight, 2019
Price NL, Miguel V, Ding W, Singh AK, Malik S, Rotllan N, Moshnikova A, Toczek J, Zeiss C, Sadeghi MM, Arias N, Baldán Á, Andreev OA, Rodríguez-Puyol D, Bahal R, Reshetnyak YK, Suárez Y, Fernández-Hernando C, Lamas S.   +18 more
europepmc   +1 more source

Loss of pericyte smoothened activity in mice with genetic deficiency of leptin. [PDF]

BMC Cell Biol, 2017
Xie G, Swiderska-Syn M, Jewell ML, Machado MV, Michelotti GA, Premont RT, Diehl AM.   +6 more
europepmc   +1 more source

Paraquat Exposure Increases Oxidative Stress Within the Dorsal Striatum of Male Mice With a Genetic Deficiency in One-carbon Metabolism. [PDF]

Toxicol Sci, 2019
Jadavji NM, Murray LK, Emmerson JT, Rudyk CA, Hayley S, Smith PD.   +5 more
europepmc   +1 more source

Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx.

Am J Physiol Lung Cell Mol Physiol
Vittal R, Walker NM, McLinden AP, Braeuer RR, Ke F, Fattahi F, Combs MP, Misumi K, Aoki Y, Wheeler DS, Wilke CA, Huang SK, Moore BB, Cao P, Lama VN.   +14 more
europepmc   +1 more source

Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol, 2019
Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, Lusis AJ.   +15 more
europepmc   +1 more source