Results 211 to 220 of about 185,305 (259)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The fitness consequences of genetic divergence between polymorphic gene arrangements. [PDF]

Genetics
Charlesworth B.
europepmc   +1 more source

Genetic divergence in turmeric genotypes

International Journal of Advanced Biochemistry Research
GB Phuke, VS Kale, AM Sonkamble, PK Nagre, PV Jadhav, YV Ingle   +5 more
openaire   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Polymorphism of Genes Potentially Affecting Growth and Body Size Suggests Genetic Divergence in Wild and Domestic Reindeer (<i>Rangifer tarandus</i>) Populations. [PDF]

Genes (Basel)
Krutikova AA, Dementieva NV, Shcherbakov YS, Goncharov VV, Griffin DK, Romanov MN.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Mitochondrial DNA evidence reflects high genetic divergence of Amynthas aspergillum (Oligochaeta: Megascolecidae) in southern China. [PDF]

Ecol Evol
Li J, Jiang J, Jin Q, Yuan Z, Qiu J.
europepmc   +1 more source

Combination of Cpb-Hsp70 typing methods reveals genetic divergence between Leishmania infantum strains causing human tegumentary leishmaniasis in northern Italy and central Spain: a retrospective study. [PDF]

Infect Dis Poverty
Gritti T, Chicharro C, Carrillo E, Solana JC, Moreno J, Carra E, Ortalli M, Morselli S, Gaspari V, Zanazzi M, Lazzarotto T, Rugna G, Varani S.   +12 more
europepmc   +1 more source

Genetic divergence and truncation and simultaneous selection in inbred families (S₁) of elephant grass for bioenergetic purposes via mixed models. [PDF]

Sci Rep
Ambrósio M, Daher RF, Silva Santana JG, Leite CL, Duarte JVB, Vidal AKF, Nascimento MR, de Souza AG, Freitas RS, Stida WF, Farias JEC, Santos RM.   +11 more
europepmc   +1 more source