Results 71 to 80 of about 185,305 (259)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Genetic divergence analysis in groundnut (ArachishypogaeaL.)
Electronic Journal of Plant Breeding, 2018 Genetic diversity among 32 genotypes of groundnut was estimated for six characters using Mahalanobis D2 statistic. The analysis of variance revealed significant differences among the genotypes for all characters.
K. Saritha +3 more
doaj +1 more source
Genetic divergence between transposable elements
Genetical Research, 1986 SummaryThe probabilities of genetic identity between different members of the same family of transposable elements in a randomly mating host population are determined, under the assumption of statistical equilibrium between neutral mutations, random genetic drift, transposition and unbiased gene conversion. The method allows for variation in numbers of
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BMC Evolutionary Biology, 2012 Background Patterns of genetic divergence between populations of facultative metallophytes have been investigated extensively. However, most previous investigations have focused on a single plant species making it unclear if genetic divergence shows ...
Ye M +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Genetic divergence and association analyses in Hedge lucerne (Desmanthus virgatus L. Willd) [PDF]
Electronic Journal of Plant Breeding, 2013 Twenty three mutants along with control of hedge lucerne variety TNDV-1 were evaluated for twelve traits to assess genetic divergence. Mutants were grouped in to eight clusters based on D2 values.
Deepthi.I.V.L, A. Kalamani and N. Manivannan
doaj
Genetic divergence analysis in Plantago germplasm
Electronic Journal of Plant Breeding, 2017 Plantago is an important medicinal plant valued for its seeds and husk which are used in indigenous medicine, all over the world. An investigation was carried out to assess the genetic divergence among 49 accessions of Plantago, comprising four species ...
Dilshad Ahmed +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source