Results 81 to 90 of about 185,305 (259)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
DIVERGÊNCIA GENÉTICA NUMA POPULAÇÃO F5 DE MELÃO
The aim of this paper was to evaluate the genetic divergence of a melon population of the Plant Breeding Program from the Federal University of Alagoas.
Marcelo Cavalcante +4 more
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Testing for selection on color and pattern in a mimetic radiation
In this paper, we analyze variation in spectral reflectance and color pattern among populations to demonstrate dramatic divergence between four distinct morphs of the mimic poison frog Ranitomeya imitator.
Justin YEAGER, Jason L. BROWN, Victor MORALES, Molly CUMMINGS5, Kyle SUMMERS
doaj
Genetic divergence and stability analysis in Pigeonpea (Cajanus cajan L.) [PDF]
Thirty Pigeonpea genotypes studied for genetic divergence using Mahalanobis D2 statistic indicated wider genetic diversity.Considerable variability was observed for days to 50% flowering, days to maturity, plant height, number of pods per plantand seed ...
Ch.Sreelakshmi, D.Shivani and C.V.Sameer Kumar
doaj
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
GROUPING OF CATINGUEIRA GENOTYPES BASED ON MORPHOLOGICAL CHARACTERISTICS
The objective of this study was to obtain information about the characteristics of Poincianella pyramidalis (Tul.) through morphological characters. We have analyzed eleven genotypes of P.
Leonardo Silva Souza +5 more
doaj +1 more source

