Results 131 to 140 of about 5,291,009 (397)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Genetic Diversity of Ampicillin-resistant Vibrio Isolated From Various Stages of Tiger Shrimp Larvae Development [PDF]

open access: yes, 2000
This research was carried out to study genetic diversity of ampicillin-resistant Vibrio from various stages of tiger shrimp larvae (Penaeus Monodon) development from,Tambak Inti Rakyat hatchery, near Labuan, West Java, Indonesia.
SUWANTO, A. (ANTONIUS)   +1 more
core  

The Effect of Strong Purifying Selection on Genetic Diversity

open access: yesGenetics, 2017
Negative selection is a ubiquitous evolutionary force, but its effects on diversity in large samples are poorly understood. Cvijović, Good, and Desai obtain simple analytical expressions for the whole population site frequency spectrum....
I. Cvijović   +2 more
semanticscholar   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

First report of Seville root-knot nematode, Meloidogyne hispanica (Nematoda: Meloidogynidae) in the USA and North America [PDF]

open access: yesJournal of Nematology, 2021
Andrea M. Skantar   +7 more
doaj   +1 more source

Hurdles and clarifications for the cultivation of saffron in Jammu and Kashmir

open access: yesJournal of Agriculture and Food Research, 2022
Since saffron is a triploid crop, it does not generate seed when selfed or crossed and is passed down through the generations by daughter corms produced from the mother corms.
Aabid M. Rather   +5 more
doaj  

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Genetic Diversity in Apricot

open access: yes, 2012
Apricot is a fruit species adopted to a wide geographical areas (De Poerderle, 1788; Loudon, 1838; Arakelyan, 1968; Mehlenbacher et al. 1991; Huxley, 1992; Butner, 2001). 173 years ago, Loudon (1838) was first to mention that wild apricots with different shades of pink flowers had been used as ornamental purpose for centuries.
Kahraman Gürcan, Kadir Ugurtan Yilmaz
openaire   +4 more sources

Diversity analysis of 80,000 wheat accessions reveals consequences and opportunities of selection footprints

open access: yesNature Communications, 2020
Genebanks hold comprehensive collections of wild species, wild relatives, and landraces that are useful for genetic improvement. Here, the authors report the genotype of nearly 80,000 wheat accessions using DArTseq technology to show the less explored ...
Carolina Sansaloni   +28 more
doaj   +1 more source

Genetic Diversity within a Global Panel of Durum Wheat (Triticum durum) Landraces and Modern Germplasm Reveals the History of Alleles Exchange

open access: yesFrontiers in Plant Science, 2017
Durum wheat is the 10th most important crop in the world, and its use traces back to the origin of agriculture. Unfortunately, in the last century only part of the genetic diversity available for this species has been captured in modern varieties through
H. Kabbaj   +8 more
semanticscholar   +1 more source

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