Genetic Diversity of Natural Populations of Bactrocera Occipitalis (Bezzi) and B. Philippinensis Drew and Hancock (Diptera: Tephritidae) in Selected Mango Producing Areas in the Philippines Using Microsatellites [PDF]
Using nine microsatellite loci, the genetic diversity of natural populations of Bactrocera occipitalis and B. philippinensis was investigated. Estimates of genetic diversity based on allele number (na and ne), heterozygosity (Ho and He) and Shannon ...
Diaz, M. G. (Maria)+4 more
core
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Genetic Diversity of Kejobong Goat Based on Mitochondrial Dna D-loop Sequence [PDF]
This study was aimed to find out the diversity of mtDNA D-loop at Kejobong goat. The completemtDNA D-loop sequence of 12 goat blood samples were analyzed from 4 different location inPurbalingga Regency, Central Java province, sub-districts Kejobong ...
Harlistyo, M. F. (M)+2 more
core
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Characterization of Vittatidera zeaphila (Nematoda: Heteroderidae) from Indiana with molecular phylogenetic analysis of the genus [PDF]
Andrea M. Skantar+5 more
doaj +1 more source
Genetic Diversity in Bradyrhizobium japonicum Serogroup 123 and Its Relation to Genotype-Specific Nodulation of Soybean [PDF]
Michael J. Sadowsky+3 more
openalex +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
THE MOLECULAR BASIS OF GENETIC DIVERSITY AMONG CYTOPLASMS OF TRITICUM AND AEGILOPS. III. CHLOROPLAST GENOMES OF THE M AND MODIFIED M GENOME-CARRYING SPECIES [PDF]
Toru Terachi+2 more
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source