Results 111 to 120 of about 3,031,778 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

DIFFERENTIATION AMONG POPULATIONS WITH MIGRATION, MUTATION, AND DRIFT: IMPLICATIONS FOR GENETIC INFERENCE [PDF]

, 2006
Seongho Song, Dipak K. Dey, Kent E. Holsinger   +2 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A total evidence approach justifies taxonomic splitting of the endangered Pecos gambusia into three species

Royal Society Open Science
Gambusia nobilis is a federally endangered species found across a fragmented distribution within the Pecos River Drainage of Texas and New Mexico, USA.
David S. Portnoy, Robert J. Bretzing-Tungate, Andrew T. Fields, Megan G. Bean, Ryan K. Smith, Elizabeth P. Dolan, Rose Blanchard, Kevin W. Conway   +7 more
doaj   +1 more source

How long do Red Queen dynamics survive under genetic drift? A comparative analysis of evolutionary and eco-evolutionary models

, 2020
Hanna Schenk, Hinrich Schulenburg, Arne Traulsen   +2 more
openalex   +1 more source

Addressing the Externalities from Genetically Modified Pollen Drift on a Heterogeneous Landscape [PDF]

, 2016
Mattia Mancini, Kent Kovacs, Eric J. Wailes, Jennie Popp   +3 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Distinguishing Genetic Drift from Selection in Papillomavirus Evolution. [PDF]

Viruses, 2023
Burk RD, Mirabello L, DeSalle R.
europepmc   +1 more source

Genetic isolation of fragmented populations is exacerbated by drift and selection [PDF]

, 2006
Yvonne Willi, Josh Van Buskirk, Bernhard Schmid, Markus Fischer   +3 more
openalex   +1 more source