Results 191 to 200 of about 234,175 (326)

Genetic Drift Versus Climate Region Spreading Dynamics of COVID-19. [PDF]

open access: yesFront Genet, 2021
Di Pietro R   +3 more
europepmc   +1 more source

Genetic Drift during Systemic Arbovirus Infection of Mosquito Vectors Leads to Decreased Relative Fitness during Host Switching [PDF]

open access: bronze, 2016
Nathan D. Grubaugh   +7 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice. [PDF]

open access: yesNat Commun
Sprockett DD   +4 more
europepmc   +1 more source

Reviewer #1 (Public review): The integrated WF-Haldane (WFH) model of genetic drift resolving the many paradoxes of molecular evolution

open access: gold
Yongsen Ruan   +8 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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