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Genetic engineering in organoids [PDF]
AbstractThree-dimensional organoids have been widely used for developmental and disease modeling. Organoids are derived from both adult and pluripotent stem cells. Various types are available for mimicking almost all major organs and tissues in the mouse and human.
Isaree Teriyapirom+2 more
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Genetic engineering and the eye. [PDF]
Abstract The transformative potential of genetic engineering in ophthalmology is remarkable, promising new treatments for a wide range of blinding eye diseases. The eye is an attractive target organ for genetic engineering approaches, in part due to its relatively immune-privileged status, its accessibility, and the ease of monitoring of ...
Murphy R, Martin KR.
europepmc +3 more sources
The arrival of genetic engineering [PDF]
The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 ...
Arulmuthu, E.+2 more
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Principles of Genetic Engineering [PDF]
Genetic engineering is the use of molecular biology technology to modify DNA sequence(s) in genomes, using a variety of approaches. For example, homologous recombination can be used to target specific sequences in mouse embryonic stem (ES) cell genomes or other cultured cells, but it is cumbersome, poorly efficient, and relies on drug positive/negative
Thomas M. Lanigan+2 more
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Genetically engineering milk [PDF]
It has been thirty years since the first genetically engineered animal with altered milk composition was reported. During the intervening years, the world population has increased from 5bn to 7bn people. An increasing demand for protein in the human diet has followed this population expansion, putting huge stress on the food supply chain.
Whitelaw, C Bruce A+4 more
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Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications
Recently, microalgal biotechnology has received increasing interests in producing valuable, sustainable and environmentally friendly bioproducts. The development of economically viable production processes entails resolving certain limitations of ...
Samir B. Grama, Zhiyuan Liu, Jian Li
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Engineering Switches, Genetically [PDF]
Ostermeier, Guntas, and Mitchel describe a new approach to design enzymes that are allosterically regulated by an unrelated ligand . The resulting protein, constructed by nonhomologous recombination and genetic screens, displays switch-like behavior.
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Research and adoption of biotechnology strategies could improve California fruit and nut crops
California's fruit and nut tree crops represent one-third of the state's cash farm receipts and 70% of U.S. fruit and nut production. Advances in crop biotechnology and genetic engineering could help protect these valuable crops from pests and diseases ...
V Haroldsen+3 more
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Human Microbiome Engineering: The Future and Beyond [PDF]
Microbial flora of skin and mucosal surface are vital component of human biology. Current research indicates that this microbial constellation, rather than being inert commensals, has greater implications in health and disease.
Arunava Kali
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