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Why do so many biologists express so little concern for biology as a whole and such contempt for fields other than their own? The current debate on release of genetically engineered organisms into the environment, specifically, J. E.
Hayden, W. John
core +4 more sources
Genetic engineering in organoids [PDF]
AbstractThree-dimensional organoids have been widely used for developmental and disease modeling. Organoids are derived from both adult and pluripotent stem cells. Various types are available for mimicking almost all major organs and tissues in the mouse and human.
Isaree Teriyapirom+2 more
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Through the advent of recombinant DNA technology, genetic engineering has emerged as a crucial step in the development of industrial bioprocesses. Accordingly, genetic engineering techniques such as molecular cloning and recombinant DNA technology, molecular manipulations, and cellular manipulations constitute the fundamental aspects of this article ...
German, E.V.+3 more
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Principles of Genetic Engineering [PDF]
Genetic engineering is the use of molecular biology technology to modify DNA sequence(s) in genomes, using a variety of approaches. For example, homologous recombination can be used to target specific sequences in mouse embryonic stem (ES) cell genomes or other cultured cells, but it is cumbersome, poorly efficient, and relies on drug positive/negative
Thomas M. Lanigan+2 more
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The arrival of genetic engineering [PDF]
The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 ...
Arulmuthu, E.+2 more
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Genetically engineering milk [PDF]
It has been thirty years since the first genetically engineered animal with altered milk composition was reported. During the intervening years, the world population has increased from 5bn to 7bn people. An increasing demand for protein in the human diet has followed this population expansion, putting huge stress on the food supply chain.
Whitelaw, C Bruce A+4 more
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Engineering Switches, Genetically [PDF]
Ostermeier, Guntas, and Mitchel describe a new approach to design enzymes that are allosterically regulated by an unrelated ligand . The resulting protein, constructed by nonhomologous recombination and genetic screens, displays switch-like behavior.
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Genetic heterogeneity analysis using genetic algorithm and network science [PDF]
Through genome-wide association studies (GWAS), disease susceptible genetic variables can be identified by comparing the genetic data of individuals with and without a specific disease. However, the discovery of these associations poses a significant challenge due to genetic heterogeneity and feature interactions.
arxiv
Code Building Genetic Programming [PDF]
In recent years the field of genetic programming has made significant advances towards automatic programming. Research and development of contemporary program synthesis methods, such as PushGP and Grammar Guided Genetic Programming, can produce programs that solve problems typically assigned in introductory academic settings.
arxiv +1 more source