Results 221 to 230 of about 5,695,316 (423)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Physiological study in Saccharomyces cerevisiae for overproduction of a homogeneous human epidermal growth factor molecule

open access: yesBiotecnología Aplicada
The epidermal growth factor (EGF) is a molecule of potent mitogenic activity that accelerates the healing of wounds and ulcers of different tissues in the human body.
Jorge Valdés   +9 more
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Genetic engineering of E. coli K-12 for heterologous carbohydrate antigen production. [PDF]

open access: yesMicrob Cell Fact
Li C   +8 more
europepmc   +1 more source

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