Results 31 to 40 of about 1,062,704 (335)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Investigating Antimicrobial Resistance and ESBL Producing Gene in Klebsiella Isolates among Neonates and Adolescents in Southern Bangladesh

Canadian Journal of Infectious Diseases and Medical Microbiology, 2022
Background. Multidrug-resistant (MDR) clones of Klebsiella pneumoniae (Kpn) have been increasingly documented in community-acquired and nosocomial infections all around the globe.
Afroza Akter Tanni, Nahid Sultana, Wazir Ahmed, Md. Mahbub Hasan, Md. Shakhawat Hossain, Sajjad Hossain Noyon, Md. Mobarok Hossain, Adnan Mannan   +7 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene

Genetics Research, 2022
POLD1 (DNA polymerase delta 1, catalytic subunit) is a protein-coding gene that encodes the large catalytic subunit (POLD1/p125) of the DNA polymerase delta (Polδ) complex.
Md. Nazmul Islam Bappy, Anindita Roy, Md Gulam Rabbany Rabbi, Nusrat Jahan, Fahmida Akther Chowdhury, Syeda Farjana Hoque, Emran Hossain Sajib, Parvez Khan, Ferdaus Mohd Altaf Hossain, Kazi Md. Ali Zinnah   +9 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Cloning of anti-HBsAg single-chain variable fragments from hybridoma cells for one-step ELISA

Biotechnology & Biotechnological Equipment, 2017
Hepatitis B virus (HBV) infection is a worldwide health problem. More than 400 million people are chronic HBV carriers in the world. Infected individuals are at a high risk of developing liver cirrhosis and hepatocellular carcinoma as the main ...
Berrin Erdag, Koray Bertan Balcioglu, Aylin Ozdemir Bahadir, Duygu Hinc, Ozlem Ibrahimoglu, Aydin Bahar, Aynur Basalp, Fatima Yucel   +7 more
doaj   +1 more source

In-Silico Exploration of Plant Metabolites as Potential Remedies of Norovirus

Advances in Virology, 2022
Research is still being carried out to develop specific medications or vaccinations to fight norovirus, a key contributor to foodborne illness. This study evaluated certain plant-based active chemicals as prospective candidates for such treatments using ...
Zenifer Alam, Md. Nazmul Islam Bappy, Abida Sultana, Fayeza Sadia Laskar, Kawsar Miah, Kazi Md. Ali Zinnah, Sudeb Saha   +6 more
doaj   +1 more source

Collective action framing genetic engineering resistance in New Zealand [PDF]

, 2011
The genetic engineering resistance movement in New Zealand constructed strategic and meaningful interpretations of why the genetic engineering technique is problematic and what can be done about it.
Tucker, C
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

California agriculture and genetic engineering

California Agriculture, 1982
California Agriculture - All ...
L Lewis
doaj