Results 41 to 50 of about 1,119,255 (298)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Dalla creazione alla programmazione. Il concetto di vita nell’era della biologia sintetica [PDF]
S&F_scienzaefilosofia.it, 2014 This paper aims to organize a reflection about the recent developing field of synthetic biology. It is structured into three main parts. The first one tries to point out the features of this emerging field (the analogies and the differences with the ...
Luca Lo Sapio
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Historical and technological development of genetic engineering in Croatia
Studia Lexicographica, 2020 The paper provides an overview of concepts and knowledge about genetic engineering and its development in Croatia and abroad from the second half of the 20th century to the present day.
Vlatka Godinić Mikulčić
doaj +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Background. Multidrug-resistant (MDR) clones of Klebsiella pneumoniae (Kpn) have been increasingly documented in community-acquired and nosocomial infections all around the globe.
Afroza Akter Tanni +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
California agriculture and genetic engineering
California Agriculture, 1982 California Agriculture - All ...
L Lewis
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Cloning of anti-HBsAg single-chain variable fragments from hybridoma cells for one-step ELISA
Biotechnology & Biotechnological Equipment, 2017 Hepatitis B virus (HBV) infection is a worldwide health problem. More than 400 million people are chronic HBV carriers in the world. Infected individuals are at a high risk of developing liver cirrhosis and hepatocellular carcinoma as the main ...
Berrin Erdag +7 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Genetic engineering of salinity-tolerant plants
California Agriculture, 1984 Not available – first paragraph follows: Molecular techniques such as recombinant DNA technology may ultimately have their most significant effect on agriculture. Recent advances raise the possibility of the development of new plant germplasm through the
R Valentine
doaj