Results 81 to 90 of about 1,062,704 (335)

An immune system based genetic algorithm using permutation-based dualism for dynamic traveling salesman problems [PDF]

open access: yes, 2009
Copyright @ Springer-Verlag Berlin Heidelberg 2009.In recent years, optimization in dynamic environments has attracted a growing interest from the genetic algorithm community due to the importance and practicability in real world applications. This paper
C. Li   +7 more
core   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Genetic engineering in athletes [PDF]

open access: yesBMJ, 2008
Athletes who want to maximise their performance are continually tempted to use illegal drugs to gain competitive advantage and to aid recovery from training and injuries. Recent revelations of widespread doping arising from investigations of the distributionof the anabolic steroid tetrahydrogestrinone by the American company BALCO (Bay Area Laboratory ...
openaire   +3 more sources

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Genetic Engineering in Bacteria, Fungi, and Oomycetes, Taking Advantage of CRISPR

open access: yesDNA
Genetic engineering has revolutionized our ability to modify microorganisms for various applications in agriculture, medicine, and industry. This review examines recent advances in genetic engineering techniques for bacteria, fungi, and oomycetes, with a
Piao Yang   +6 more
doaj   +1 more source

Improved Quantum Genetic Algorithm in Application of Scheduling Engineering Personnel

open access: yesAbstract and Applied Analysis, 2014
To verify the availability of the improved quantum genetic algorithm in solving the scheduling engineering personnel problem, the following work has been carried out: the characteristics of the scheduling engineering personnel problem are analyzed, the ...
Huaixiao Wang   +4 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Futurenatural? A future of science through the lens of wisdom [PDF]

open access: yes, 1999
This is a PDF version of an article published in Heythrop Journal© 1999. The definitive version is available at www.blackwell-synergy.com.This article discusses genetic engineering and Christian theories of wisdom, particularly in relation in creation ...
Deane-Drummond, Celia
core  

Complexation of DNA with Cationic Surfactant

open access: yes, 1999
Transfection of an anionic polynucleotide through a negatively charged membrane is an important problem in genetic engineering. The direct association of cationic surfactant to DNA decreases the effective negative charge of the nucleic acid, allowing the
Akhtar   +30 more
core   +2 more sources

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