Results 171 to 180 of about 2,077,052 (339)

Evaluating human genetic support for hypothesized metabolic disease genes

, 2022
Peter Dornbos, Preeti Singh, Dongkeun Jang, Anubha Mahajan, Sudha B. Biddinger, Jerome I. Rotter, Mark I. McCarthy, Jason Flannick   +7 more
openalex   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of inclusion or non-inclusion of short lactations and cow and/or dam genetic group on genetic evaluation of Girolando dairy cattle

, 2016
Ali William Canaza-Cayo, Marcos Vinícius Gualberto Barbosa da Silva, Jaime Araújo Cobuci, Marta Fonseca Martins, Paulo Sávio Lopes   +4 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Genetic evaluation of sudden unexpected death in infants and children. [PDF]

Eur J Pediatr
Pries AM, van der Crabben SN, Moll HA, Rijdt WPT, Verbruggen KT, Puiman PJ, PESUDIC collaborative.   +6 more
europepmc   +1 more source

Women cotton farmers: Their perceptions and experiences with transgenic varieties: A case study for Colombia [PDF]

This paper explores gender differences in cotton cultivation and looks into the perceptions and experiences of women and men with transgenic varieties.
Cardona, Iván, Fonseca, Luz Amparo, Maldonado, Jorge H., Mendoza, Sandra L., Ruiz, Lorena, Zambrano, Patricia   +5 more
core  

Genetic Algorithms: Genesis of Stock Evaluation

, 2004
Rama Prasad Kanungo
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Comparison of linear and threshold models for genetic evaluation of morphological defects in Nellore cattle. [PDF]

J Anim Sci
Campos MAF, Oliveira HR, Mulim HA, Oliveira EDS, Hidalgo J, Costa RB.   +5 more
europepmc   +1 more source