Results 171 to 180 of about 17,950,884 (399)

Evaluation of the genetic stability of the temperature-sensitive PB2 gene mutation of the influenza A/Ann Arbor/6/60 cold-adapted vaccine virus [PDF]

, 1994
John J. Treanor, Mark D. Perkins, Rosalyn Battaglia, B R Murphy   +3 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Genetic and Environmental Factors in Dairy Sire Evaluation. III. Influence of Environmental and Other Extraneous Correlations Among the Daughters

, 1965
B. Bereskin, Jay L. Lush
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Effects of genetic and environmental variance on dairy sire evaluation

, 1963
B. Bereskin
openalex   +1 more source

Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline.

Journal of Cardiac Failure, 2018
R. Hershberger, M. Givertz, Carolyn Y. Ho, D. Judge, P. Kantor, K. McBride, A. Morales, Matthew R. G. Taylor, M. Vatta, S. Ware   +9 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Avaliação genética de touros pelo modelo animal, modelo touro e método das companheiras de rebanho Sire evaluation by animal model, sire model and contemporary herdmate method

Revista Brasileira de Zootecnia, 1999
As capacidades previstas de transmissão (PTA) para a produção de leite de 529 touros, usando o modelo animal (MA), modelo touro (MT) e o método das companheiras de rebanho (MCR), foram calculadas e comparadas por meio da correlação de ordem e valores, da
Rui da Silva Verneque, Mário Luiz Martinez, Roberto Luiz Teodoro, Amaury Alípio Pimentel, William José Ferreira   +4 more
doaj  

Genetic components of potato chip quality evaluated in three environments and under various storage regimes [PDF]

, 1992
D. R. Lynch, G. C. C. Tai, Robert Coffin
openalex   +1 more source