Results 251 to 260 of about 17,950,884 (399)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Comparative Evaluation of the Acute Toxic Effects in Monkeys, Pigs and Mice of a Genetically EngineeredSalmonellaStrain (VNP20009) Being Developed as an Antitumor Agent [PDF]

open access: bronze, 2000
King C. Lee   +9 more
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

GENETIC SELECTION | Evaluation and Methods [PDF]

open access: yes, 2002
G.R. Wiggans, N. Gengler
openaire   +1 more source

Clinical and genetic evaluation of hereditary myopathies in an adult Saudi cohort. [PDF]

open access: yesBMC Neurol
Alhammad RM   +4 more
europepmc   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Access to genetic evaluation of 1463 individuals with orofacial cleft in Brazil. [PDF]

open access: yesJ Pediatr (Rio J)
Silva IMW   +8 more
europepmc   +1 more source

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