Results 221 to 230 of about 4,927,397 (250)

Genetic evolution analysis of PRRSV ORF5 gene in five provinces of Northern China in 2024. [PDF]

BMC Vet Res
Jian Y, Lu C, Shi Y, Kong X, Song J, Wang J.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Phylogenetic analysis and genetic evolution of porcine respiratory coronavirus in Guangxi province, Southern China from 2022 to 2024. [PDF]

Front Microbiol
Shi Y, Shi K, Yin Y, Feng S, Long F, Lu W, Qu S, Ma Y, He J.   +8 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Genetic evolution of swine vesicular disease viruses circulating in Italy from 1992 to the eradication in 2015 and emergence of a recent recombinant strain. [PDF]

Virus Evol
Bregoli A, Benedetti D, Calzolari M, Benevenia R, Di Nardo A, Castelli A, Corsa M, Grazioli S, Chiapponi C, Brocchi E, Pezzoni G.   +10 more
europepmc   +1 more source

Genetic evolution and relapse-associated mutations in adult T-cell acute lymphoblastic leukemia patients treated in PETHEMA trials. [PDF]

Hemasphere
González-Gil C, Lopes T, Morgades M, Fuster-Tormo F, Montesinos P, Medina CR, Hermosín L, González-Martínez T, Queipo MP, González-Campos J, Martínez-Sánchez P, Díaz-Beya M, Coll R, Maluquer C, Zamora L, Artola T, Vall-Llovera F, Tormo M, Torrent A, Martínez-Laperche C, Gil-Cortés C, Barba P, Cervera M, Ribera J, Fernández-Delgado M, Ayala R, Cladera A, Mateos MC, Vidal MJ, Feliu J, Torres A, Azaceta G, Calasanz MJ, Bigas A, Esteller M, Orfao A, Ribera JM, Genescà E.   +37 more
europepmc   +1 more source

Molecular Epidemiology and Genetic Evolution Analysis of Porcine Reproductive and Respiratory Syndrome Virus in Southern Xinjiang, China, from 2023 to 2025. [PDF]

Vet Sci
Liu S, Hou M, Chen X, Ma B, Zhang Z, Guo M, Chen Y, Li L.   +7 more
europepmc   +1 more source

Analysis of the genetic evolution and recombination of the PRRSV-2 GP2 protein in China from 1996 to 2023. [PDF]

Microbiol Spectr
Liu K, Lv C, He C, Pang J, Lai C, Chen S, Wang R, Kong W, Ma J, Zhao M.   +9 more
europepmc   +1 more source

Characterization of SARS-CoV-2 intrahost genetic evolution in vaccinated and non-vaccinated patients from the Kenyan population. [PDF]

J Virol
Lugano D, Mwangi K, Mware B, Kibet G, Osiany S, Kiritu E, Dobi P, Muli C, Njeru R, de Oliveira T, Njenga MK, Routh A, Oyola SO.   +12 more
europepmc   +1 more source

Genetic Evolution of Pediatric Acute Myeloid Leukemia and Its Contribution to Disease Relapse

Umeda M, Kolekar P, Huskey AL, Suryaprakash S, Ma J, Li H, Westover T, Walsh MP, Song G, Liu Y, Tran Q, Balagopal V, Wang L, Brady SW, Pounds S, Mead PE, Karol SE, Inaba H, Rubnitz JE, Ribeiro R, Ma X, Klco JM.   +21 more
europepmc   +1 more source