Results 241 to 250 of about 1,500,618 (293)

Molecular Epidemiology and Genetic Evolution of Porcine Reproductive and Respiratory Syndrome Virus in Northern China During 2021-2023. [PDF]

Viruses
Yuan N, Yang Z, Lv F, Dou L, Li X, Zhao B, Dong S.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Genetic Evolution of Antibiotic Resistance and Virulence Genes in <i>Escherichia coli</i> Isolates from a Chinese Hospital over a 12-Year Period. [PDF]

Microorganisms
Feng C, Jia H, Yang Q, Zou Q.
europepmc   +1 more source

Genome-wide expanding of genetic evolution and potential pathogenicity in Vibrio alginolyticus. [PDF]

Emerg Microbes Infect
Huang Z, Li Y, Yu K, Ma L, Pang B, Qin Q, Li J, Wang D, Gao H, Kan B.   +9 more
europepmc   +1 more source

Highly pathogenic bovine viral diarrhea virus BJ-11 unveils genetic evolution related to virulence in calves. [PDF]

Front Microbiol
Zhang Y, Cheng J, Guo Y, Hu Y, Zhao Z, Liu W, Zhou L, Wu P, Cheng C, Yang C, Yang J, Du E, Li Y.   +12 more
europepmc   +1 more source

SARS-CoV-2 excretion and genetic evolution in nasopharyngeal and stool samples from primary immunodeficiency and immunocompetent pediatric patients. [PDF]

Virol J
Khemiri H, Ben Fraj I, Lorusso A, Mekki N, Mangone I, Gdoura M, Di Pasqual A, Cammà C, Di Lollo V, Cherni A, Touzi H, Sadraoui A, Meddeb Z, Hogga N, Ben Mustapha I, Barbouche MR, Ouederni M, Triki H, Haddad-Boubaker S.   +18 more
europepmc   +1 more source

Large-scale metagenomic assembly provide new insights into the genetic evolution of gut microbiomes in plateau ungulates. [PDF]

NPJ Biofilms Microbiomes
Xu B, Song P, Jiang F, Cai Z, Gu H, Gao H, Li B, Liang C, Qin W, Zhang J, Yan J, Liu D, Sun G, Zhang T.   +13 more
europepmc   +1 more source

The first complete mitochondrial genome of Grossulariaceae: Molecular features, structure recombination, and genetic evolution. [PDF]

BMC Genomics
Lu G, Wang W, Zhang S, Yang G, Zhang K, Que Y, Deng L.   +6 more
europepmc   +1 more source

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The Genetic Evolution of Metastasis

Cancer Research, 2022
Abstract Cancer is an evolutionary process that is characterized by the emergence of multiple genetically distinct populations or clones within the primary tumor. Intratumor heterogeneity provides a substrate for the selection of adaptive clones, such as those that lead to metastasis.
Aljosja Rogiers, Irene Lobon, Lavinia Spain, Samra Turajlic   +3 more
openaire   +2 more sources

The evolution of genetic diversity

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1979
Abstract The existence within natural populations of large amounts of genetic variation in molecules and morphology presents an evolutionary problem. The ‘neutralist’ solution to this problem, that the variation is usually unimportant to the organisms displaying it, has now lost much of its strength.
openaire   +2 more sources