Results 101 to 110 of about 3,869,150 (303)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ciência Animal Brasileira, 2013 (Co)variances, heritability and genetics change were estimated for weight at 120 (W120), 210 (W210), 365 (W365), 450 (W450) and 550 (W550 ) days of age in Nellore cattle from the Humid Tropical region of Brazil. A total of 65,876 records of animals born
Thaymisson Santos de Lira +5 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Genetic trends in the Zimbabwe’s national maize breeding program over two decades
Frontiers in Plant ScienceMonitoring genetic gains within breeding programs is a critical component for continuous improvement. While several national breeding programs in Africa have assessed genetic gain using era studies, this study is the first to use two decades of ...
Ronica Mukaro +26 more
doaj +1 more source
Genetic architecture of rainbow trout survival from egg to adult [PDF]
, 2010 Survival from birth to a reproductive adult is a challenge that only robust individuals resistant to a variety of mortality factors will overcome. To assess whether survival traits share genetic architecture throughout the life cycle, we estimated ...
Paananen, T. +5 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Environmental Research Letters, 2018 For highly productive regions such as Germany, the increase of wheat grain yields observed throughout the 20th century is largely attributed to the progress in crop breeding and agronomic management. However, several studies indicate a strong variability
H E Ahrends +6 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Ciência Rural, 1996 Foi conduzido um experimento a campo nos anos de 1993 e 1994, em Eldorado do Sul-RS, com o objetivo de estimar a herdabilidade dos caracteres ciclo, da emergência até o florescimento, e estatura de planta em aveia, para aumentar a eficiência da seleção ...
Adriane Leite do Amaral +4 more
doaj +1 more source