Results 111 to 120 of about 1,195,293 (349)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Genetic yield gains of winter wheat in Germany over more than 100 years (1895–2007) under contrasting fertilizer applications

Environmental Research Letters, 2018
For highly productive regions such as Germany, the increase of wheat grain yields observed throughout the 20th century is largely attributed to the progress in crop breeding and agronomic management. However, several studies indicate a strong variability
H E Ahrends, W Eugster, T Gaiser, V Rueda-Ayala, H Hüging, F Ewert, S Siebert   +6 more
doaj   +1 more source

Improving Genetic Gain with Genomic Selection in Autotetraploid Potato

The Plant Genome, 2016
Potato (Solanum tuberosum L.) breeders consider a large number of traits during cultivar development and progress in conventional breeding can be slow. There is accumulating evidence that some of these traits, such as yield, are affected by a large number of genes with small individual effects.
Slater, Anthony T., Cogan, Noel O. I., Forster, John W., Hayes, Benjamin J., Daetwyler, Hans D.   +4 more
openaire   +5 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Integrating genomic selection into dairy cattle breeding programmes: a review

Animal, 2013
Extensive genetic progress has been achieved in dairy cattle populations on many traits of economic importance because of efficient breeding programmes.
A. Bouquet, J. Juga
doaj  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Diallel crossing in Pinus cembra : IV. Age trends in genetic parameters and genetic gain for growth and branching traits [PDF]

Annals of Forest Research, 2008
This paper reports results from a complete 10 x 10 diallel carried out in a natural population of Swiss stone pine (Pinus cembra L.) from the southern Carpathian Mountains.
Ioan Blada, Flaviu Popescu
doaj  

Realized Genetic Gain and Seed Source X Site Interaction on 1.8 Cineole Content and Oil Yield of Cajuput [PDF]

, 2016
Realized genetic gain of improved seed of cajuput from a breeding program and seed source x site interaction on the oil properties (1,8-cineole and oil yield) was evaluated through the establishment of genetic gain trials in two sites: Gunungkidul dan ...
Kartikawati, N. K. (Noor), Prastyono, P. (Prastyono), Rimbawanto, A. (Anto)   +2 more
core  

Inbreeding management and optimization of genetic gain with phenotypic and genomic selection in oil palm (Elaeis guineensis)[W776] [PDF]

, 2020
Oil palm breeding relies on reciprocal recurrent selection between two heterotic groups complementary for bunch number and average bunch weight. Given the long generation interval and the limited selection intensity imposed by the progeny tests currently
Cros, David, Sanchez, Leopoldo, Tchounke, Billy   +2 more
core  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source