Results 111 to 120 of about 6,603,978 (370)

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Genetic trends in the Zimbabwe’s national maize breeding program over two decades

Frontiers in Plant Science
Monitoring genetic gains within breeding programs is a critical component for continuous improvement. While several national breeding programs in Africa have assessed genetic gain using era studies, this study is the first to use two decades of ...
Ronica Mukaro, Davison Chaingeni, Clay Sneller, Jill E. Cairns, Lennin Musundire, Boddupalli M. Prasanna, Busiso Olga Mavankeni, Biswanath Das, Mable Mulanya, Walter Chivasa, Xavier Mhike, Xavier Mhike, Thokozile Ndhlela, Thokozile Ndhlela, Nakai Matongera, Nakai Matongera, Prince Muchapondwa Matova, Prince Muchapondwa Matova, Dean Muungani, Dean Muungani, Charles Mutimaamba, Charles Mutimaamba, Dagne Wegary, Mainassara Zaman-Allah, Cosmos Magorokosho, Victor Chingwara, Dumisani Kutywayo   +26 more
doaj   +1 more source

A brief history of research on the genetics of alcohol and other drug use disorders. [PDF]

, 2014
ObjectiveThis article reviews developments in research on genetic influences on alcohol and other drug use and disorders over the past 7 decades.MethodThe author began with a review of the flow and content of articles published in the three iterations of
Schuckit, Marc A
core   +2 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Controlling Coancestry and Thereby Future Inbreeding by Optimum-Contribution Selection Using Alternative Genomic-Relationship Matrices

Frontiers in Genetics, 2020
We tested the consequences of using alternative genomic relationship matrices to predict genomic breeding values (GEBVs) and control of coancestry in optimum contribution selection, where the relationship matrix used to calculate GEBVs was not ...
G. T. Gebregiwergis, Anders C. Sørensen, Mark Henryon, Mark Henryon, Theo Meuwissen   +4 more
doaj   +1 more source

Iron Age and Anglo-Saxon genomes from East England reveal British migration history [PDF]

, 2016
British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population.
A Sajantila, AL Topf, AW Briggs, B Winney, C Capelli, CT O'Dushlaine, D Petts, G Jun, GB Busby, H Eckardt, H Härke, H Jònsson, H Li, H Li, HX Zheng, I Lazaridis, J Hines, J Montgomery, J Novembre, JK Pickrell, M Meyer, M Schubert, ME Weale, MG Thomas, N Patterson, N Rohland, P Balaresque, P Brotherton, P Budd, P Ralph, P Skoglund, PR Staab, S Besenbacher, S Leslie, S Schiffels, T Sundell, W Haak, Wellcome Trust   +37 more
core   +2 more sources

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Pedigree relationships to control inbreeding in optimum-contribution selection realise more genetic gain than genomic relationships

Genetics Selection Evolution, 2019
We tested the premise that optimum-contribution selection with pedigree relationships to control inbreeding (POCS) realises at least as much true genetic gain as optimum-contribution selection with genomic relationships (GOCS) at the same rate of true ...
M. Henryon, Huiming Liu, P. Berg, P. Berg, G. Su, H. Nielsen, G. Gebregiwergis, A. Sørensen   +7 more
semanticscholar   +1 more source

Predicted genetic gain and realised gain in stand volume of Eucalyptus globulus [PDF]

Tree Genetics & Genomes, 2012
Realised gains in stand volume of Eucalyptus globulus Labill. families at 7–9 years were compared with gains predicted at 3.5 years. Gain predictions were based on height, diameter at breast height (DBH), sectional area, and stem volume for 153 full-sib families and 18 commercial checks in five-tree line plots on three West Australian sites.
Callister, AN, England, N, Collins, S
openaire   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source