Results 61 to 70 of about 945,528 (300)

A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer [PDF]

open access: yes, 2019
The response of metastatic colorectal cancer (mCRC) to the first-line conventional combination therapy is highly variable, reflecting the elevated heterogeneity of the disease.
Belardinilli, Francesca   +29 more
core   +2 more sources

Genetic response to environmental heterogeneity

open access: yesNature, 1974
Uploaded by Plazi for TaxoDros. We do not have abstracts.
J F, McDonald, F J, Ayala
openaire   +3 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Dystonic hyperkinesias in children of early childhood

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Dystonic hyperkinesias in children of early childhood may beinvolved in the structure of many syndromes that have differentetiological factors, prognosis, and treatment.
M. Yu. Bobylova   +7 more
doaj   +1 more source

New Insights into Genetics of Endometriosis—A Comprehensive Literature Review

open access: yesDiagnostics, 2023
This comprehensive review explores the genetic contributions to endometriosis and their potential impact on improving diagnostic techniques. The review begins by defining endometriosis and discussing its prevalence, emphasizing the need for a deeper ...
Diana Maria Chiorean   +6 more
doaj   +1 more source

Local-scale patterns of genetic variability, outcrossing, and spatial structure in natural stands of Arabidopsis thaliana [PDF]

open access: yes, 2015
As Arabidopsis thaliana is increasingly employed in evolutionary and ecological studies, it is essential to understand patterns of natural genetic variation and the forces that shape them.
Bomblies, Kirsten   +7 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Neurodegeneration with brain iron accumulation

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Neurodegeneration with brain iron accumulation (NBIA) is aclinically and genetically heterogeneous group of hereditary (predominantlyautosomal recessive) progressive disorders of the CNSwith a common feature of iron accumulation in basal ganglia ...
G. E. Rudenskaya, E. Yu. Zakharova
doaj   +1 more source

Genome-wide association study identifies common and low-frequency variants at the AMHgene locus that strongly predict serum AMH levels in males [PDF]

open access: yes, 2016
Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females.
Day, Felix R.   +5 more
core   +1 more source

Genetic heterogeneity in multiple myeloma [PDF]

open access: yesLeukemia, 2004
In the past decade, many progresses have been made in our knowledge of the genetics of multiple myeloma. The use of molecular cytogenetic techniques has led to the identification of several recurrent (cyto)genetic abnormalities, representing either prognostic markers, or novel therapeutic targets.
F, Magrangeas   +4 more
openaire   +2 more sources

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