Results 21 to 30 of about 7,541,678 (261)

Autosomal dominant tubulointerstitial kidney disease: Diagnostic challenges in the absence of genetic testing. A case report

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2023
Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a group of rare uncommon genetic disorders characterized by tubular damage and interstitial fibrosis in the absence of glomerular lesions.
L. Surzhko, V. Nepomnyashchy
doaj   +1 more source

Why do we keep ignoring sex in kidney disease? [PDF]

open access: yes, 2023
Disparity; Pharmacokinetics; WomenDisparidad; Farmacocinética; MujeresDisparitat; Farmacocinètica; DonesThroughout the history of nephrology, little attention has been paid to the sex and gender differences in kidney disease.
Torra Balcells, Roser   +10 more
core   +1 more source

Genetic identification of inherited cystic kidney diseases for implementing precision medicine: a study protocol for a 3-year prospective multicenter cohort study

open access: yesBMC Nephrology, 2021
Background Inherited cystic kidney disease is a spectrum of disorders in which clusters of renal cysts develop as the result of genetic mutation. The exact methods and pipelines for defining genetic mutations of inherited cystic kidney disease are not ...
Hayne Cho Park   +18 more
doaj   +1 more source

Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans [PDF]

open access: yes, 2008
Includes abstract.Includes bibliographical references (leaves 226-256).Obesity is a worldwide problem and is a factor in the pathogenesis of the metabolic syndrome and kidney disease through the development of obesity-related hypertension and ...
Okpechi, Ikechi Gareth
core   +1 more source

Current status and prospects of diagnosis and treatment of genetic kidney diseases in Chinese children [PDF]

open access: yesZhenduanxue lilun yu shijian
Genetic kidney diseases refer to a broad category of renal disorders associated with genetic etiologies. They are the leading cause of end-stage kidney disease in children and adolescents,accounting for over 25% of pediatric patients requiring renal ...
SHEN Qian
doaj   +1 more source

Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis [PDF]

open access: yes, 2013
Aims: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil.
Tsuneto, Luiza Tamie   +13 more
core   +1 more source

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]

open access: yes, 2011
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
Polonikov, Alexey   +75 more
core   +1 more source

Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2023
Hanny Sawaf,1 Tariku T Gudura,1 Sylvester Dorobisz,1 Dianne Sandy,2 Xiangling Wang,1 Shane A Bobart2 1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, USA; 2Department of Kidney Medicine, Cleveland Clinic Florida, Weston, FL ...
Sawaf H   +5 more
doaj  

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function [PDF]

open access: yes, 2015
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining ...
Atkinson, Elizabeth J   +999 more
core   +2 more sources

Genitourinary defects, anxiety and aggressive-like behavior and glucose metabolism disorders in Zmym2 mutant mice with inserted piggyBac transposon

open access: yesFrontiers in Cell and Developmental Biology
Mutations in ZMYM2 lead to syndromic congenital anomalies of the kidney and urinary tract (CAKUT) in humans. Tbx18 is co-expressed with Zmym2 in mesenchymal compartment of developing mouse ureter, indicating a potential in vivo relevance of the TBX18 ...
Rufeng Dai   +12 more
doaj   +1 more source

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