Results 91 to 100 of about 2,465,783 (307)

A high density linkage map of the bovine genome

BMC Genetics, 2009
Background Recent technological advances have made it possible to efficiently genotype large numbers of single nucleotide polymorphisms (SNPs) in livestock species, allowing the production of high-density linkage maps.
Coppieters Wouter, Fisher Paul, Keehan Mike, Arias Juan A, Spelman Richard   +4 more
doaj   +1 more source

Linkage Mapping and Comparative Genomics of Red Drum (Sciaenops ocellatus) Using Next-Generation Sequencing

G3: Genes, Genomes, Genetics, 2017
Developments in next-generation sequencing allow genotyping of thousands of genetic markers across hundreds of individuals in a cost-effective manner. Because of this, it is now possible to rapidly produce dense genetic linkage maps for nonmodel species.
Christopher M. Hollenbeck, David S. Portnoy, Dana Wetzel, Tracy A. Sherwood, Paul B. Samollow, John R. Gold   +5 more
doaj   +1 more source

A second-generation genetic linkage map for bighead carp (Aristichthys nobilis) based on microsatellite markers

, 2014
Bighead carp (Aristichthys nobilis) is an important aquaculture fish worldwide. Genetic linkage maps for the species were previously reported, but map resolution remained to be improved.
Yu, X., Liu, L., Tong, J., Fu, B., Zhu, C., Liu, H., Wang, X., Sun, Y., Guo, W., Feng, X.   +9 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

High-Density Genetic Linkage Map Construction and Quantitative Trait Locus Mapping for Hawthorn (Crataegus pinnatifida Bunge)

Scientific Reports, 2017
Genetic linkage maps are an important tool in genetic and genomic research. In this study, two hawthorn cultivars, Qiujinxing and Damianqiu, and 107 progenies from a cross between them were used for constructing a high-density genetic linkage map using ...
Yuhui Zhao, Kai Su, Gang Wang, Liping Zhang, Jijun Zhang, Junpeng Li, Yinshan Guo   +6 more
doaj   +1 more source

Near-saturated and complete genetic linkage map of black spruce (Picea mariana)

BMC Genomics, 2010
Background Genetic maps provide an important genomic resource for understanding genome organization and evolution, comparative genomics, mapping genes and quantitative trait loci, and associating genomic segments with phenotypic traits.
Mann Ishminder K, Kang Bum-Yong, Major John E, Rajora Om P   +3 more
doaj   +1 more source

Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide Approach [PDF]

, 2008
Background: The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for ...
Daetwyler, Hans D., Daetwyler Hans D., Villanueva, Beatriz, Daetwyler, HD, Woolliams, John A., Hans D Daetwyler, John A Woolliams, Villanueva Beatriz, Daetwyler, H.D., Woolliams John A., Woolliams, JA, Villanueva, B., Beatriz Villanueva, Villanueva, B, Woolliams, J.A.   +14 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

First High-Density Linkage Map and Single Nucleotide Polymorphisms Significantly Associated With Traits of Economic Importance in Yellowtail Kingfish Seriola lalandi

Frontiers in Genetics, 2018
The genetic resources available for the commercially important fish species Yellowtail kingfish (YTK) (Seriola lalandi) are relative sparse. To overcome this, we aimed (1) to develop a linkage map for this species, and (2) to identify markers/variants ...
Nguyen H. Nguyen, Pasi M. A. Rastas, H. K. A. Premachandra, Wayne Knibb   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source