Results 91 to 100 of about 342,848 (311)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The use of different clustering methods in the evaluation of genetic diversity in upland cotton
Revista Ciência AgronômicaThe continuous development and evaluation of new genotypes through crop breeding is essential in order to obtain new cultivars. The objective of this work was to evaluate the genetic divergences between cultivars of upland cotton (Gossypium hirsutum L ...
Laíse Ferreira de Araújo +4 more
doaj +1 more source
Scientific Reports, 2017 Genetic linkage maps are an important tool in genetic and genomic research. In this study, two hawthorn cultivars, Qiujinxing and Damianqiu, and 107 progenies from a cross between them were used for constructing a high-density genetic linkage map using ...
Yuhui Zhao +6 more
doaj +1 more source
A high density linkage map of the bovine genome
BMC Genetics, 2009 Background Recent technological advances have made it possible to efficiently genotype large numbers of single nucleotide polymorphisms (SNPs) in livestock species, allowing the production of high-density linkage maps.
Coppieters Wouter +4 more
doaj +1 more source
Construction of a comparative genetic map in faba bean (Vicia faba L.); conservation of genome structure with Lens culinaris [PDF]
, 2008 Background The development of genetic markers is complex and costly in species with little pre-existing genomic information. Faba bean possesses one of the largest and least studied genomes among cultivated crop plants and no gene-based genetic maps ...
Carmen M. Avila +31 more
core +2 more sources
G3: Genes, Genomes, Genetics, 2017 Developments in next-generation sequencing allow genotyping of thousands of genetic markers across hundreds of individuals in a cost-effective manner. Because of this, it is now possible to rapidly produce dense genetic linkage maps for nonmodel species.
Christopher M. Hollenbeck +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
On the complexity of hierarchical problem solving [PDF]
, 2005 Competent Genetic Algorithms can efficiently address problems in which the linkage between variables is limited to a small order k. Problems with higher order dependencies can only be addressed efficiently if further problem properties exist that can be ...
Edwin D. de Jong +5 more
core +1 more source
Near-saturated and complete genetic linkage map of black spruce (
BMC Genomics, 2010 Background Genetic maps provide an important genomic resource for understanding genome organization and evolution, comparative genomics, mapping genes and quantitative trait loci, and associating genomic segments with phenotypic traits.
Mann Ishminder K +3 more
doaj +1 more source