Results 81 to 90 of about 2,465,783 (307)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

An integrated genetic linkage map for white clover (Trifolium repens L.) with alignment to Medicago

, 2013
Background: White clover (Trifolium repens L.) is a temperate forage legume with an allotetraploid genome (2n=4×=32) estimated at 1093 Mb. Several linkage maps of various sizes, marker sources and completeness are available, however, no integrated map ...
Franzmayr, Benjamin K, Griffiths, Andrew G, Simon, Deborah, Khan, Anar K, Hancock Kerry R., Barrett, Brent A, Bickerstaff, Paul, Jones, Chris S, Anderson, Craig B   +8 more
core   +1 more source

Construction of a comparative genetic map in faba bean (Vicia faba L.); conservation of genome structure with Lens culinaris [PDF]

, 2008
Background The development of genetic markers is complex and costly in species with little pre-existing genomic information. Faba bean possesses one of the largest and least studied genomes among cultivated crop plants and no gene-based genetic maps ...
Carmen M. Avila, Serafin Cruz-Izquierdo, Avila, C.M., Ellwood, Simon, Cruz-Izquierdo, Serafin, Hane, J.K., Megan Jordan, Phan Huyen TT, Huyen T.T. Phan, Torres Anna M, Torres, A.M., Jordan, Megan, James K. Hane, Oliver, R.P., Simon R. Ellwood, Richard P. Oliver, Hane James, Oliver, Richard P., Oliver Richard P, Ellwood, S.R., Phan, Huyen T.T., Torres, Anna M., Anna M. Torres, Ellwood Simon R, Cruz-Izquierdo Serafín, Hane, James, Avila Carmen M, Cruz-Izquierdo, S., Avila, Carmen M., Jordan Megan, Phan, H.T.T., Jordan, M.   +31 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Assortative Mating and Linkage Disequilibrium

G3: Genes, Genomes, Genetics, 2017
Assortative mating has been suggested to result in an increase in heritability and additive genetic variance through an increase in linkage disequilibrium.
Philip W. Hedrick
doaj   +1 more source

A population genetics model of marker-assisted selection [PDF]

, 1997
A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations.
Luo, Z. W., Woolliams, J. A., Luo, Z.W., Woolliams, John, Thompson, R.   +4 more
core  

A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensisn l-converting enzyme (ACE) unlinked to the ACE gene [PDF]

, 2008
Background: angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on ...
Amy Luke, Zhu, Xiaofeng, Xiaofeng Zhu, Terrence E Forrester, Forrester, Terrence E., Nourdine Bouzekri, Cooper, Richard S., Bouzekri Nourdine, Colin A McKenzie, McKenzie, Coiln A., Forrester Terrence E, Zhu Xiaofeng, McKenzie Colin A, Adeyemo, Adebowale A., Luke Amy, Bouzekri, Nourdine, Cooper Richard S, Richard S Cooper, Luke, Amy, Adebowale A Adeyemo, Adeyemo Adebowale A   +20 more
core   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The use of different clustering methods in the evaluation of genetic diversity in upland cotton

Revista Ciência Agronômica
The continuous development and evaluation of new genotypes through crop breeding is essential in order to obtain new cultivars. The objective of this work was to evaluate the genetic divergences between cultivars of upland cotton (Gossypium hirsutum L ...
Laíse Ferreira de Araújo, Wener Santos de Almeida, Cândida Hermínia Campos de Magalhães Bertini, Francisco das Chagas Vidal Neto, Ervino Bleicher   +4 more
doaj   +1 more source