Results 81 to 90 of about 612,083 (305)

Models and partition of variance for quantitative trait loci with epistasis and linkage disequilibrium

open access: yesBMC Genetics, 2006
Background A genetic model about quantitative trait loci (QTL) provides a basis to interpret the genetic basis of quantitative traits in a study population, such as additive, dominance and epistatic effects of QTL and the partition of genetic variance ...
Wang Tao, Zeng Zhao-Bang
doaj   +1 more source

Estimation of linkage disequilibrium in a sample of the United Kingdom dairy cattle population using unphased genotypes [PDF]

open access: yes, 2003
The association between genetic marker alleles was estimated for two regions of the bovine genome from a random sample of 50 young dairy bulls born in the United Kingdom between 1988 and 1995. Microsatellite marker genotypes were obtained for six markers
Knott, S A   +5 more
core  

SLiM: Simulating Evolution with Selection and Linkage [PDF]

open access: yes, 2013
SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for ...
Messer, Philipp W.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An Ultra-High-Density, Transcript-Based, Genetic Map of Lettuce. [PDF]

open access: yes, 2013
We have generated an ultra-high-density genetic map for lettuce, an economically important member of the Compositae, consisting of 12,842 unigenes (13,943 markers) mapped in 3696 genetic bins distributed over nine chromosomal linkage groups.
Ashrafi, Hamid   +10 more
core   +1 more source

Resultants in genetic linkage analysis

open access: yesJournal of Symbolic Computation, 2006
Statistical models for genetic linkage analysis of k-locus diseases are k-dimensional subvarieties of a (3^k-1)-dimensional probability simplex. We determine the algebraic invariants of these models with general characteristics for k=1, in particular we recover, and generalize, the Hardy-Weinberg curve.
Hallgrímsdóttir, Ingileif B.   +1 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

High-Density Genetic Linkage Map Construction and Quantitative Trait Locus Mapping for Hawthorn (Crataegus pinnatifida Bunge)

open access: yesScientific Reports, 2017
Genetic linkage maps are an important tool in genetic and genomic research. In this study, two hawthorn cultivars, Qiujinxing and Damianqiu, and 107 progenies from a cross between them were used for constructing a high-density genetic linkage map using ...
Yuhui Zhao   +6 more
doaj   +1 more source

Determinants of variation in serum paraoxonase enzyme activity in baboons

open access: yesJournal of Lipid Research, 2005
Paraoxonase (PON), an HDL-associated enzyme, is one of many circulating antioxidants thought to play a vital protective role. To better understand the determinants of quantitative variation in serum PON activity, we assayed PON in samples from 611 ...
David L. Rainwater   +5 more
doaj   +1 more source

Genome mapping of tetraploid cotton : towards a saturated and unified map [PDF]

open access: yes, 2004
DNA-based genetic maps have been produced in nearly all major crop species, thus facilitating the analysis of genome structure and evolution, and improving efficiency and accuracy of breeding.
Bojinov, B.   +4 more
core  

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