Results 71 to 80 of about 616,649 (304)
Robust Tests in Genome-Wide Scans under Incomplete Linkage Disequilibrium [PDF]
, 2009 Under complete linkage disequilibrium (LD), robust tests often have greater power than Pearson's chi-square test and trend tests for the analysis of case-control genetic association studies.
Geller, Nancy +4 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A genetic linkage map and comparative mapping of the prairie vole (
BMC Genetics, 2011 Background The prairie vole (Microtus ochrogaster) is an emerging rodent model for investigating the genetics, evolution and molecular mechanisms of social behavior. Though a karyotype for the prairie vole has been reported and low-resolution comparative
Young Larry J +3 more
doaj +1 more source
Construction of High-Density Linkage Maps of Populus deltoides × P. simonii Using Restriction-Site Associated DNA Sequencing. [PDF]
PLoS ONE, 2016 Although numerous linkage maps have been constructed in the genus Populus, they are typically sparse and thus have limited applications due to low throughput of traditional molecular markers. Restriction-site associated DNA sequencing (RADSeq) technology
Chunfa Tong +11 more
doaj +1 more source
What does it take to evolve behaviorally complex organisms? [PDF]
, 2001 What genotypic features explain the evolvability of organisms that have to accomplish many different tasks? The genotype of behaviorally complex organisms may be more likely to encode modular neural architectures because neural modules dedicated to ...
Calabretta, Raffaele +3 more
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Linkage to chromosome 11p12 in two Maltese families with a highly penetrant form of osteoporosis [PDF]
, 2007 Osteoporosis is a metabolic bone disease with a strong genetic component. Family-based linkage studies were performed by a number of investigators to try to identify loci that might contain genes responsible for an increased susceptibility to ...
Brincat, Mark P. +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Cleft Lip Palate and Craniofacial Anomalies, 2017 Introduction: Nonsyndromic cleft lip and/or palate (NSCLP) occurs as a result of multifactorial determinants, involving both genetic and environmental factors.
Nurul Syazana Mohamad Shah +3 more
doaj +1 more source
Accounting for a quantitative trait locus for plasma triglyceride levels: utilization of variants in multiple genes. [PDF]
PLoS ONE, 2012 For decades, research efforts have tried to uncover the underlying genetic basis of human susceptibility to a variety of diseases. Linkage studies have resulted in highly replicated findings and helped identify quantitative trait loci (QTL) for many ...
Lisa J Martin +2 more
doaj +1 more source
A Genetic Linkage Map Using an F1 Population in Rubber Tree (Hevea brasiliensis) based on microsatellite markers. P0527 [PDF]
, 2012 The construction of molecular gene linkage map in Hevea requires specific methodology because of high heterozygosity. Unlike annual crops, a cross between two heterozygous parents in Hevea can yield information up to four alleles, which are segregated ...
Garcia, Antonio Augusto Franco +7 more
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