Results 51 to 60 of about 616,649 (304)
Research and Practice in Thrombosis and HaemostasisBackground: The plasma protein histidine-rich glycoprotein (HRG) interacts with multiple plasma ligands with various roles in coagulation, immunity, and angiogenesis.
Mary I. Underwood +9 more
doaj +1 more source
Genetic linkage and molecular evolution [PDF]
Current Biology, 2001 The different models make similar predictions which makes it difficult to ascribe an observation to just one process. Are there any observations that allow one to identify which process is operating? It turns out that the distribution of frequencies of neu-tral variants in a sample of sequences (the frequency spectrum) is model-dependent.
Gordo, Isabel, Charlesworth, Brian
openaire +2 more sources
Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder. [PDF]
, 2014 BackgroundAutism spectrum disorders (ASDs) are male-biased and genetically heterogeneous. While sequencing of sporadic cases has identified de novo risk variants, the heritable genetic contribution and mechanisms driving the male bias are less understood.
Cantor, Rita M +5 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Investigating chromosomal structural variations in Musa acuminate using NGS approaches : [W077] [PDF]
, 2014 Structural heterozygosity is thought to be one of the main causes of sterility in banana (Musa spp.) hybrids. These structural variations impact chromosomal segregation and recombination, limiting crossing possibilities and complicating genetic analyses.
Baurens, Franc-Christophe +7 more
core
Genome sequence and genetic linkage analysis of Shiitake mushroom _Lentinula edodes_ [PDF]
, 2012 _Lentinula edodes_ (Shiitake/Xianggu) is an important cultivated mushroom. Understanding the genomics and functional genomics of _L. edodes_ allows us to improve its cultivation and quality.
Chun Hang Au +10 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Multiparental mapping of plant height and flowering time QTL in partially isogenic sorghum families. [PDF]
, 2014 Sorghum varieties suitable for grain production at temperate latitudes show dwarfism and photoperiod insensitivity, both of which are controlled by a small number of loci with large effects.
Assaranurak, I +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Scientific Reports, 2017 Genetic linkage maps are indispensable tools in a wide range of genetic and genomic research. With the advancement of genotyping-by-sequencing (GBS) methods, the construction of a high-density linkage maps has become achievable in marine organisms ...
Hongtao Nie +7 more
doaj +1 more source