X-LINKAGE OF A HUMAN GENETIC LOCUS THAT CORRECTS THE DNA SYNTHESIS LESION IN tsC1AGOH MOUSE CELLS [PDF]
Richard E. Giles, Frank H. Ruddle
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Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
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The application of linkage analysis to genetic counselling in families with Duchenne or Becker muscular dystrophy. [PDF]
Shirley Hodgson+7 more
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De novo construction of polyploid linkage maps using discrete graphical models
Linkage maps are used to identify the location of genes responsible for traits and diseases. New sequencing techniques have created opportunities to substantially increase the density of genetic markers.
Behrouzi, Pariya, Wit, Ernst C.
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Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
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Autosomal genetic maps of the Australian Sheep Blowfly,Lucilia cuprina dorsalisR.-D. (Diptera: Calliphoridae), and possible correlations with the linkage maps ofMusca domesticaL. andDrosophila melanogaster(Mg.) [PDF]
G. G. Foster+4 more
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Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
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Q fever outbreak in the terraced vineyards of Lavaux, Switzerland
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini+9 more
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Genetic locus (stmF) associated with cyclic GMP phosphodiesterase activity in Dictyostelium discoideum maps in linkage group II [PDF]
M. B. Coukell, A. M. Cameron
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