Results 171 to 180 of about 612,083 (305)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic linkage mapping in Megathyrsus maximus (Jacq.) with multiple dosage markers. [PDF]

open access: yesG3 (Bethesda)
Gesteira GS   +9 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Association of autoimmune comorbidities in persons with multiple sclerosis from a population-based study with genetic linkage. [PDF]

open access: yesMult Scler J Exp Transl Clin
Gnavi R   +12 more
europepmc   +1 more source

QTL mapping for growth-related traits by constructing the first genetic linkage map in Simao pine. [PDF]

open access: yesBMC Plant Biol, 2022
Wang D   +8 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Exposing Selection and Genetic Linkage in the Evolutionary Enigmatic Balanced Lethal System in <i>Triturus</i> Newts. [PDF]

open access: yesEcol Evol
Meilink WRM   +7 more
europepmc   +1 more source

Analysis of the Genome Sequence of Strain GiC-126 of Gloeostereum incarnatum with Genetic Linkage Map. [PDF]

open access: yesMycobiology, 2021
Jiang WZ   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy