Results 181 to 190 of about 342,848 (311)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Genetic linkage mapping in Megathyrsus maximus (Jacq.) with multiple dosage markers. [PDF]

open access: yesG3 (Bethesda)
Gesteira GS   +9 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Association of autoimmune comorbidities in persons with multiple sclerosis from a population-based study with genetic linkage. [PDF]

open access: yesMult Scler J Exp Transl Clin
Gnavi R   +12 more
europepmc   +1 more source

QTL mapping for growth-related traits by constructing the first genetic linkage map in Simao pine. [PDF]

open access: yesBMC Plant Biol, 2022
Wang D   +8 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Exposing Selection and Genetic Linkage in the Evolutionary Enigmatic Balanced Lethal System in <i>Triturus</i> Newts. [PDF]

open access: yesEcol Evol
Meilink WRM   +7 more
europepmc   +1 more source

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