Results 181 to 190 of about 612,083 (305)

Genetic linkage in mental illness [PDF]

Nature, 1990
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Genetic linkage disequilibrium of deleterious mutations in threatened mammals. [PDF]

EMBO Rep
Hu C, Liu G, Zhang Z, Pan Q, Zhang X, Liu W, Li Z, Li M, Zhu P, Ji T, Garber PA, Zhou X.   +11 more
europepmc   +1 more source

Close genetic linkage between human and companion animal extraintestinal pathogenic Escherichia coli ST127. [PDF]

Curr Res Microb Sci, 2022
Elankumaran P, Browning GF, Marenda MS, Reid CJ, Djordjevic SP.   +4 more
europepmc   +1 more source

Genetic Linkage Analysis [PDF]

, 2020
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Timescale and genetic linkage explain the variable impact of defense systems on horizontal gene transfer. [PDF]

Genome Res
Liu Y, Botelho J, Iranzo J.
europepmc   +1 more source

QTL mapping and identification of genes associated with the resistance to Acanthoscelides obtectus in cultivated common bean using a high-density genetic linkage map. [PDF]

BMC Plant Biol, 2022
Li X, Tang Y, Wang L, Chang Y, Wu J, Wang S.   +5 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Construction of an ultrahigh-density genetic linkage map for Manihot esculenta Crantz and identification of QTL for root quantity traits. [PDF]

BMC Plant Biol
Liu Q, Li Z, Wang Z, Lu Y, Jiang S, Xia C, An P, Zhao L, Deng K, Xia Z, Wang W.   +10 more
europepmc   +1 more source