Results 11 to 20 of about 342,848 (311)

A genetic linkage map of Venturia inaequalis, the causal agent of apple scab [PDF]

open access: yes, 2009
Background Venturia inaequalis is an economically-important disease of apple causing annual epidemics of scab worldwide. The pathogen is a heterothallic ascomycete with an annual cycle of sexual reproduction on infected apple leaf litter, followed by ...
Sargent, Daniel J.   +17 more
core   +1 more source

Progress in Genetic Studies of Tourette’s Syndrome

open access: yesBrain Sciences, 2017
Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time.
Yanjie Qi   +3 more
doaj   +1 more source

High-density multi-population consensus genetic linkage map for peach. [PDF]

open access: yesPLoS ONE, 2018
Highly saturated genetic linkage maps are extremely helpful to breeders and are an essential prerequisite for many biological applications such as the identification of marker-trait associations, mapping quantitative trait loci (QTL), candidate gene ...
Cassia da Silva Linge   +7 more
doaj   +1 more source

The first-generation Daphnia magna linkage map [PDF]

open access: yes, 2010
Background Daphnia magna is a well-established model species in ecotoxicology, ecology and evolution. Several new genomics tools are presently under development for this species; among them, a linkage map is a first requirement for estimating the genetic
Ebert, Dieter   +14 more
core   +1 more source

Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion [PDF]

open access: yes, 1998
Linkage disequilibrium has been a powerful tool in identifying rare disease alleles in human populations. To date, most research has been directed to isolated populations which have undergone a bottleneck followed by rapid exponential expansion.
Zöllner, Sebastian   +8 more
core   +1 more source

Deciphering the mystery of CHNG3 [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism
Congenital hypothyroidism (CH), characterized by insufficient thyroid hormone production due to abnormalities in the hypothalamic-pituitary-thyroid axis, is the most common congenital endocrine disorder.
Satoshi Narumi
doaj   +1 more source

Linkage map construction involving a reciprocal translocation [PDF]

open access: yes, 2010
This paper is concerned with a novel statistical–genetic approach for the construction of linkage maps in populations obtained from reciprocal translocation heterozygotes of barley (Hordeum vulgare L.).
Cistué, L.   +16 more
core   +1 more source

Linkage Analysis [PDF]

open access: yes, 2021
The process of linkage analysis in humans requires a statistical framework in which various hypotheses about the linkage of a trait locus and marker locus can be considered in an observational study design.
Blanton, Susan H, Susan H. Blanton
core   +1 more source

Genetic Linkage Analysis [PDF]

open access: yesArchives of Neurology, 1999
Genetic linkage analysis is a powerful tool to detect the chromosomal location of disease genes. It is based on the observation that genes that reside physically close on a chromosome remain linked during meiosis. For most neurologic diseases for which the underlying biochemical defect was not known, the identification of the chromosomal location of ...
openaire   +2 more sources

Three-point appraisal of genetic linkage maps [PDF]

open access: yes, 2012
This paper develops a simple diagnostic for the investigation of uncertainty within genetic linkage maps using a Bayesian procedure. The method requires only the genotyping data and the proposed genetic map, and calculates the posterior probability for ...
Gilks, W R   +9 more
core   +1 more source

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