Progress in Genetic Studies of Tourette’s Syndrome
Brain Sciences, 2017 Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time.
Yanjie Qi +3 more
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High-density multi-population consensus genetic linkage map for peach. [PDF]
PLoS ONE, 2018 Highly saturated genetic linkage maps are extremely helpful to breeders and are an essential prerequisite for many biological applications such as the identification of marker-trait associations, mapping quantitative trait loci (QTL), candidate gene ...
Cassia da Silva Linge +7 more
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Diversity, genetic mapping, and signatures of domestication in the carrot (Daucus carota L.) genome, as revealed by Diversity Arrays Technology (DArT) markers [PDF]
, 2013 Carrot is one of the most economically important vegetables worldwide, but genetic and genomic resources supporting carrot breeding remain limited. We developed a Diversity Arrays Technology (DArT) platform for wild and cultivated carrot and used it to ...
Allender, Charlotte J. +11 more
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Deciphering the mystery of CHNG3 [PDF]
Annals of Pediatric Endocrinology & MetabolismCongenital hypothyroidism (CH), characterized by insufficient thyroid hormone production due to abnormalities in the hypothalamic-pituitary-thyroid axis, is the most common congenital endocrine disorder.
Satoshi Narumi
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Genetic Linkage Analysis [PDF]
Archives of Neurology, 1999 Genetic linkage analysis is a powerful tool to detect the chromosomal location of disease genes. It is based on the observation that genes that reside physically close on a chromosome remain linked during meiosis. For most neurologic diseases for which the underlying biochemical defect was not known, the identification of the chromosomal location of ...
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A saturated genetic linkage map of autotetraploid alfalfa (Medicago sativa L.) developed using genotyping-by-sequencing is highly syntenous with the Medicago truncatula genome. [PDF]
, 2014 A genetic linkage map is a valuable tool for quantitative trait locus mapping, map-based gene cloning, comparative mapping, and whole-genome assembly. Alfalfa, one of the most important forage crops in the world, is autotetraploid, allogamous, and highly
Acharya, Ananta +5 more
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Construction of Genetic Linkage Map of Plum (Prunus salicina L.) with ISSR and SRAP Markers
Guangdong nongye kexue, 2022 【Objective】Plum (Prunus salicina L.) is a tree species with great economic prospect in northeast China, and it has important social and economic values. Genetic linkage maps of plum were constructed by molecular markers to provide a theoretical basis for
Lili SUN +4 more
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Resultants in genetic linkage analysis
Journal of Symbolic Computation, 2006 Statistical models for genetic linkage analysis of k-locus diseases are k-dimensional subvarieties of a (3^k-1)-dimensional probability simplex. We determine the algebraic invariants of these models with general characteristics for k=1, in particular we recover, and generalize, the Hardy-Weinberg curve.
Ingileif B. Hallgrímsdóttir +1 more
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A comparison of SNPs and microsatellites as linkage mapping markers: lessons from the zebra finch (Taeniopygia guttata) [PDF]
, 2010 Background: Genetic linkage maps are essential tools when searching for quantitative trait loci (QTL). To maximize genome coverage and provide an evenly spaced marker distribution a combination of different types of genetic marker are sometimes used.
Ball, A.D. +5 more
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Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion [PDF]
, 1998 Linkage disequilibrium has been a powerful tool in identifying rare disease alleles in human populations. To date, most research has been directed to isolated populations which have undergone a bottleneck followed by rapid exponential expansion.
Laan, Maris +3 more
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