Results 261 to 270 of about 342,848 (311)

A Genetic Linkage Map for the Zebrafish

Science, 1994
To facilitate molecular genetic analysis of vertebrate development, haploid genetics was used to construct a recombination map for the zebrafish Danio ( Brachydanio ) rerio .
John H. Postlethwait, Stephen L. Johnson, Clare N. Midson, William S. Talbot, Michael Gates, Eric W. Ballinger, Dana Africa, Rebecca Andrews, Tim Carl, Judith S. Eisen, Sally Horne, Charles B. Kimmel, Mark Hutchinson, Michele Johnson, Andre Rodriguez   +14 more
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Genetic Linkage in Bipolar Disorder

CNS Spectrums, 2003
AbstractBipolar disorder is an etiologically complex syndrome that is dearly heritable. Multiple, genes, working singly or in concert, are likely to cause susceptibility to bipolar disorder. Bipolar disorder genetics has progressed rapidly in the last few decades. However, specific causal genetic mutations for bipolar disorder have not been identified.
Carol A, Mathews, Victor I, Reus
openaire   +2 more sources

Genetics and linkage analysis on phosphoglucomutase

Humangenetik, 1971
The current study is based on 454 families with 843 children from two different areas in Western Germany (Marburg and Tfibingen). Only families which have been especially ascertained for these investigations have been taken into account. For the estimation of the gene frequencies 1449 unrelated persons from the areas mentioned above were investigated ...
G G, Wendt, H, Ritter, I, Zilch, G, Tariverdian, G, Utermann, I, Kindermann, G, Kirchberg   +6 more
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Linkage Analysis of Genetic Disorders

2003
Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process.
E W, Taylor, J, Xu, E W, Jabs, D A, Meyers   +3 more
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Genetic linkage.

British journal of hospital medicine, 1986
Not all doctors would understand the statement "linkage is now established between a DNA marker and the locus for adult polycystic kidney disease at a recombination fraction of 5%". Yet over the next few years increasing numbers of DNA markers linked to single-gene disorders will become available and clinicians will need to identify patients who could ...
J R, Yates, J M, Connor
openaire   +1 more source

Bootstrapping in human genetic linkage

Annals of Human Genetics, 1994
SUMMARYLinkage analysis of discrete Mendelian traits has made a major contribution to the mapping of the human genome. However, in more complex situations, particularly Mendelian disorders showing locus heterogeneity, linkage results have sometimes been misleading.
M N, Chiano, J R, Yates
openaire   +2 more sources

A study of genetic linkage in schizophrenia

Psychological Medicine, 1987
SynopsisFamilies with more than one member affected by schizophrenia were identified and their members were interviewed. Four standardized diagnostic definitions (PSE, DSM-III, ICD-9, Feighner) were applied to all subjects who were classified as schizophrenic or not schizophrenic according to each definition.
B, Andrew, D C, Watt, C, Gillespie, H, Chapel   +3 more
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Introduction to Genetic Linkage Analysis

Cancer Investigation, 1997
Advances in molecular methodology have resulted in the successful genetic mapping and isolation of the genes responsible for numerous simple Mendelian disorders such as cystic fibrosis, neurofibromatosis, and Huntington disease. Recently, researchers have begun to successfully study diseases with more complex inheritance, such as breast cancer.
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Software for genetic linkage analysis

Molecular Biotechnology, 1996
Recent developments in human genetic linkage analysis have included the appearance of new software and collections of data and program resources, accessible by means of the Internet. Many of these new programs and collections are described, including their availability, literature background, and specific technical information.
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Gene linkage and genetic deafness

International Journal of Pediatric Otorhinolaryngology, 1995
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Cremers, C.W.R.J., Brown, S.D.M., Steel, K.P., Brunner, H.G., Read, A., Kimberling, W.J.   +5 more
openaire   +6 more sources