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Gene linkage and genetic deafness
International Journal of Pediatric Otorhinolaryngology, 1995Item does not contain ...
Cremers, C.W.R.J. +5 more
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The Use of Linkage in Genetic Counselling
Human Heredity, 1970Methods are outlined for incorporating information from genetical linkage in the prediction of genotypes, for discrimination of genetic entities, for advice to adults, and for antenatal diagnosis ...
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Linkage and Association to Genetic Markers
2015Genetic markers that are sufficiently polymorphic (as measured by their heterozygosities) can be used in linkage and association analyses to detect Mendelian segregation underlying disease phenotypes. Each type of analysis can either be based on a specific genetic model or not make any assumptions about the mode of inheritance of the disease ...
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Genetic hemochromatosis and HLA linkage
Human Genetics, 1987We previously reported five families with primary, genetic (idiopathic) hemochromatosis in whom HLA typing of subjects indicated that a homozygous-heterozygous mating had almost certainly occurred and in whom inheritance of the disease trait was best explained by an autosomal recessive mode of inheritance.
Powell, Lawrie W. +5 more
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Software for genetic linkage analysis
Molecular Biotechnology, 1996Recent developments in human genetic linkage analysis have included the appearance of new software and collections of data and program resources, accessible by means of the Internet. Many of these new programs and collections are described, including their availability, literature background, and specific technical information.
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Optimizing exact genetic linkage computations
Proceedings of the seventh annual international conference on Research in computational molecular biology, 2003Genetic linkage analysis is a challenging application which requires Bayesian networks consisting of thousands of vertices. Consequently, computing the probability of data, which is needed for learning linkage parameters, using exact computation procedures calls for an extremely efficient implementation that carefully optimizes the order of ...
Maáyan Fishelson, Dan Geiger
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Genetic linkage in the Norway rat
Genetica, 1987The present status of research on genetic linkage is reviewed. Where possible, the data are statistically combined to give consolidated estimates of the recombination value. Ten groups of linked genes have been determined. The first assignments of linkage groups to specific chromosomes have been facilitated by inter-species cell hybridisation.
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Genetic Linkage in Neurologic Diseases
New England Journal of Medicine, 1987Until recently, the hope of identifying genes associated with dominant inherited neurologic disorders seemed remote. Now that has changed. The powerful techniques of molecular biology have provided methods for locating, by linkage analysis, the genes responsible for several of these diseases and for using the same techniques for presymptomatic or ...
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The Search for Genetic Linkage in Schizophrenia
British Journal of Psychiatry, 1982Enormous industry has been devoted during the last half-century to establishing the genetic contribution to the aetiology of schizophrenia. Demonstration of a familial concentration of the disorder among the blood relatives of schizophrenics is supported by the differential concordance for schizophrenia found between monozygotic and dizygotic twins ...
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The Linkage Tree Genetic Algorithm
2010We introduce the Linkage Tree Genetic Algorithm (LTGA), a competent genetic algorithm that learns the linkage between the problem variables. The LTGA builds each generation a linkage tree using a hierarchical clustering algorithm. To generate new offspring solutions, the LTGA selects two parent solutions and traverses the linkage tree starting from the
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